Concentrations of Macrophage Inflammatory Proteins MIP-1a and MIP-1? and Interleukin 8 (Il-8) in Lyme Borreliosis

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• 作者：S. Grygorczuk ; S. Pancewicz ; J. Zajkowska ; M. Kondrusik ; R. ?wierzbi¨½ska and T. Hermanowska-Szpakowicz
• 刊名：Infection
• 出版年：2004
• 出版时间：December 2004
• 年：2004
• 卷：32
• 期：6
• 页码：350-355
• 全文大小：396 KB

文摘

Background: Components of the spirochete Borrelia burgdorferi sensu lato (B. burgdorferi s.l.) do not have chemotactic activity. However, B. burgdorferi s.l. causes a chemotactic response, probably by stimulating synthesis of cytokines of the chemokine family by host cells. Our aim was to confirm that the synthesis of chemokines is increased in Lyme borreliosis and that they may account for leukocyte migration, thus being involved in inflammatory response.