Massive anterior chamber involvement after Intra-arterial chemotherapy for retinoblastoma: ultrasound biomicroscopy and histopathology

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• 作者：Sonia De Francesco (1)
  Francesco Pichi (2)
  Andrea Lembo (2)
  Domenico Mastrangelo (3)
  Anna Paradiso (4)
  Mariacarla De Luca (1)
  Paolo Toti (5)
  Paolo Nucci (2)
  Theodora Hadjistilianou (1)
  
• 关键词：Anterior chamber retinoblastoma ; Ultrasound Biomicroscopy ; Pseudohypopion
• 刊名：International Ophthalmology
• 出版年：2014
• 出版时间：August 2014
• 年：2014
• 卷：34
• 期：4
• 页码：967-970
• 全文大小：385 KB
• 参考文献：1. Pichi F, Lembo A, De Luca M, Hadjistilianou T, Nucci P (2013) Bilateral retinoblastoma: Clinical presentation, management and treatment. Int Ophthalmol. 33(5):589鈥?93 CrossRef
  2. Haik BG, Dunleavy SA, Cooke C, Ellsworth RM, Abramson DH, Smith ME et al (1987) Retinoblastoma with anterior chamber extension. Ophthalmology 94(4):367鈥?70 CrossRef
  3. Moulin AP, Gaillard MC, Balmer A, Munier FL (2012) Ultrasound biomicroscopy evaluation of anterior extension in retinoblastoma: A clinicopathological study. Br J Ophthalmol 96(3):337鈥?40 CrossRef
  4. Vasquez LM, Giuliari GP, Halliday W, Pavlin CJ, Gallie BL, H茅on E (2011) Ultrasound biomicroscopy in the management of retinoblastoma. Eye (Lond) 25(2):141鈥?47 CrossRef
  5. Longmuir Susannah Q, Syed Nasreen A, Culver Boldt H (2010) Diffuse Anterior Retinoblastoma without Retinal Involvement. Ophthalmology 117:2034鈥?038 CrossRef
  6. Zigiotti GL, Cavarretta S, Morara M, Nam SM, Ranno S, Pichi F, Lembo A, Lupo S, Nucci P, Meduri A (2012) Standard enucleation with aluminium oxide implant (bioceramic) covered with patient鈥檚 sclera. ScientificWorldJournal. 2012:481584 CrossRef
  
• 作者单位：Sonia De Francesco (1)
  Francesco Pichi (2)
  Andrea Lembo (2)
  Domenico Mastrangelo (3)
  Anna Paradiso (4)
  Mariacarla De Luca (1)
  Paolo Toti (5)
  Paolo Nucci (2)
  Theodora Hadjistilianou (1)
  
  1. Retinoblastoma Referral Center, University of Siena, Siena, Italy
  2. San Giuseppe Hospital, University Eye Clinic, Via San Vittore 12, 20123, Milan, Italy
  3. Department of Biomedical Sciences, University of Siena, Siena, Italy
  4. Department of Ophthalmology, University of Siena, Siena, Italy
  5. Department of Human Pathology and Oncology, University of Siena, Siena, Italy
  
• ISSN：1573-2630

文摘

This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance. UBM may represent an important diagnostic tool in retinoblastoma, when the decision about enucleation of the eye must be made in the absence of histopathologic data.