A glassy carbon electrode modified with an amphiphilic, electroactive and photosensitive polymer and with multi-walled carbon nanotubes for simultaneous determination of dopamine and paracetamol

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• 作者：Ren Liu ; Xuebiao Zeng ; Jingcheng Liu ; Jing Luo ; Yuanyi Zheng…
• 刊名：Microchimica Acta
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：183
• 期：5
• 页码：1543-1551
• 全文大小：695 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Analytical Chemistry
  Inorganic Chemistry
  Physical Chemistry
  Characterization and Evaluation Materials
  Monitoring, Environmental Analysis and Environmental Ecotoxicology
  
• 出版者：Springer Wien
• ISSN：1436-5073
• 卷排序：183

文摘

The article describes an electrochemical sensor for simultaneous determination of dopamine (DA) and paracetamol (PAT). It is based on the use of an electroactive polymer (referred to as BPVCM) to functionalize multi-walled carbon nanotubes. BPVCM is a branched amphiphilic photo-sensitive and electroactive polymer that was obtained by copolymerization of a vinyl benzylcarbazole, maleic acid anhydride, 4-vinylbenzylthiol and a vinylbenzyloxycoumarin. BPVCM efficiently disperses MWCNT in aqueous solution. The electropolymerization of the carbazole moieties of the BPVCM enhances the current response. It also facilitates electron transfer in the MWCNT-BPVCM hybrid as evidenced by cyclic voltammetry and electrochemical impedance spectroscopy. A glassy carbon electrode modified with the nanocomposite displays outstanding electrocatalytic activity towards DA and PAT. DA can be determined, best at a working voltage of 0.2 V (vs. SCE), in the 5 to 1000 μM concentration range with a 2.3 μM detection limit. PAT can be determined in parallel, at a working voltage of 0.39 V (vs. SCE), in the same concentration range with a 3.5 μM detection limit. This analytical range of this method is wider than that of most alternative methods.