Role of colostrum in gastrointestinal infections

详细信息    查看全文

• 作者：Pawan Rawal (1)
  Vineet Gupta (1)
  B. R. Thapa (1)
  
• 关键词：Colostrum ; Bovine colostrum ; GI infections
• 刊名：The Indian Journal of Pediatrics
• 出版年：2008
• 出版时间：September 2008
• 年：2008
• 卷：75
• 期：9
• 页码：917-921
• 全文大小：164KB
• 参考文献：1. Kaushik S, Trivedi SS, Jain A, Bhattcharjee J. Unusual changes in colostrum composition in lactating Indian women having medical complication during pregnancy-A pilot study. / Indian J Clin Biochem 2002; 17: 68-3. CrossRef
  2. Pakkanen R, Aalto J. Review paper-Growth factors and antimicrobial factors in bovine colostrum. / Internat Diary J 1997; 7: 285-97. CrossRef
  3. Boesman-Finkelstein M, Finkelstein R. Passive oral immunization in children. / Lancet 1989; 2: 1336. CrossRef
  4. Dicthtelmuller W, Lissner R. Antibodies from colostrum in oral immunotherapy. / J Clin Biochem 1990; 28: 19-3.
  5. Ogra SS, Ogra PL. Immunological aspects of human colostrum and milk. / J Pediatr 1978; 92: 546-49. CrossRef
  6. Antonius C M., van Hoojidonk, Kussendrager K D, Steijns J M. In vivo antimicrobial and antiviral activity of components in bovine mild and colostrum involved in non-specific defence. / Br J Nutr 2000; 84 (S-1): S127–S134.
  7. Davidson G, Whyte P, Daniels E / et al. Passive immunization of children with bovine colostrum containing antibodies to human rotavirus. / Lancet 1989; 2: 709-12. CrossRef
  8. Bitzan M M, Gold B D, Phil Pott D J / et al. Inhibition of H pylori and Helicobactor mustelae binding to lipid receptors by bovine colostrum. / J Infect Dis 1998; 177: 955-61.
  9. Bogstedt A K, Johansen K, Hatta H / et al. Passive immunity against diarrhea. / Acta Pediatr 1996; 85: 125-28. CrossRef
  10. Lonnedal B, Iyer S. Lactoferrin molecular structure and biological function. / Ann Review Nutr 1995; 15: 93-00. CrossRef
  11. Bocc V, Von Breeman K, Corradeschi F / et al. What is the role of cytokines in human colostrum? / J Bio Regulat Homeo Agents 1991; 3: 121-24.
  12. Lawton J W, Shortstride K F, Wong R Ng Mh. Interferon synthesis by human Colostral leucocytes. / Arch Dis childhood 1979; 54: 127-30.
  13. Bhora F, Dinkin B, Batzri S / et al. Effect of growth factors on cell proliferation and epithelization in human skin. / J Surg Res 1995; 59: 236-44. CrossRef
  14. Francis G, Upton F, Ballard J / et al. Insulin like growth factors 1 and 2 in bovine colostrums. / J Biochem 1988; 251: 95-03.
  15. Thapa B R. Health factors in colostrum. / Indian J Pediatr 2005; 72: 579-81. CrossRef
  16. Mero A, Kahkonen, Nykanen T / et al. IGF-I, IgA and IgG responses to bovine colostrums supplementation during training. / J Appl Physiol 2002; 93: 732-39.
  17. Bocc V, Von Bremen K, Corradeschi F / et al. What is the role of cytokines in human colostrum? / J Bio Regulat Homeo Agents 1991; 3: 121-24.
  18. Ahmed L, Nazrul Islam SK, Khan NI, Nahid SN. Vitamin C Content in Human Milk (Colostrum, Transitional and Mature) and serum of a sample of Bangladeshi Mothers. / Mal J Nutr 2004; 10: 1-.
  19. Mitra A K, Mahatanabis D, Ashraf H / et al. Hyperimmune cow colostrums reduces diarrhea due to rotavirus: a doubleblind, controlled clinical trial. / Acta Pediatr 1995; 84: 996-001. CrossRef
  20. Sarkar S A, Casswall T H, Mahalanabis D-em class="a-plus-plus">et al. Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatr Infect Dis J 1998, 17: 1149-154. CrossRef
  21. Brussow H. Hilpert H. Walther I. Sidoti J. Mietens C. Bachmann P. Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis. J Clin Microbiol 1987; 25: 982-86.
  22. Tzipori S, Roberson D, Chapman C. Remission of diarrhea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrums. BMJ 1986; 293: 1276-277. CrossRef
  23. Tzipori S, Robertson D, Cooper DA, While L. Chronic cryposporidial diarrhea and hyperimmue cow colostrums. / Lancet 1987; 2: 344-45. CrossRef
  24. Nord J, Ma P, Dijohn D, Tzipori S, Tacket Co. Treatment with bovine hyperimmune colostrums of cryptosporidial diarrhea in AIDS patients. / AIDS 1990; 4: 581-84. CrossRef
  25. Ungar BL, Ward DJ, Fayer R, Quinn CA. Cessation of Cryprosporidium-associated diarrhea in an acquired immunodeficiency syndrome patient after treatment with hyperimmune bovine colostrums. / Gastroenterology 1990; 98: 486-89.
  26. Rump JA, Amdt R, Arnold A, Bendick C, Dichtelmuller H. Franke M / et al. Treatment of diarrhea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrums. / Clin Invest 1992; 70: 588-94. CrossRef
  27. Lissner R, Schmidit H, Karch H. A standard immunoglobulin preparation produced from bovine colostra shows antibody reactivity and neutralization activity against shiga like toxin and EHEC hemolysin of Escherichia coli 0157: H7. / J Infection 1996; 24: 378-83. CrossRef
  28. Huppertz, HI, Rutkowski S, Busch DH / et al. Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, shiga toxin producing / E. coli and / E. coli expressing intimin and hemolysin. / J Pediatr Gastroenterol Nutr 1999; 29: 452-56. CrossRef
  29. Bolke E, Jehle PM, Hausmann F / et al. Preoperative oral application of immunoglobulin-enriched colostrum milk and mediator response during abdominal surgery. / Shock 2002; 17: 9-2. CrossRef
  30. Bolke E, Orth K, Jehle PM / et al. Enteral application of immunoglobulin-enriched colostrum milk preparation for reducing endotoxin translocation and acute phase response in patients undergoing coronary bypass surgery-a randomized placebo controlled trial. / Wien Klin Wochenschr 2002; 114: 923-28.
  
• 作者单位：Pawan Rawal (1)
  Vineet Gupta (1)
  B. R. Thapa (1)
  
  1. Division of Pediatric Gastroenterology, Department of Gastroenterology, Post Graduate Institute Medical Education and Research (PGIMER), Chandigarh, India
  

文摘

Colostrum is breast milk produced after the birth of the newborn and lasts for 2- days. Colostrum is very important part of breast milk and lays down the immune system and confers growth factors and other protective factors for the young ones in mammals. This is the source of passive immunity transferred to the baby from the mother. The biological value of bovine colostrum in present day medical practice is documented in clinical trials and large databases containing case reports and anecdotal findings. The main actions include an antibacterial effect and modulation of immune response with the ability to neutralize lipopolysaccharides arising from gram negative bacterial pathogens. It has been found to be effective in infantile hemorrhagic diarrheas, other diarrheas and reduces the likelihood of disease progressing to hemolytic uremic syndrome. It has also been tested in H pylori infection and diarrhea in immunodeficiency. Side effects of clinical relevance are limited to possible intolerance due to lactose and sensitivity to milk proteins.