Age determination of vessel wall hematoma in spontaneous cervical artery dissection: A multi-sequence 3T Cardiovascular Magnetic resonance study

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• 作者：Maximilian Habs (1)
  Thomas Pfefferkorn (2)
  Clemens C Cyran (1)
  Jochen Grimm (1)
  Axel Rominger (3)
  Marcus Hacker (3)
  Christian Opherk (2)
  Maximilian F Reiser (1)
  Konstantin Nikolaou (1)
  Tobias Saam (1)
  
• 关键词：CMR ; internal carotid artery dissection ; vertebral artery dissection ; hematoma ; stroke
• 刊名：Journal of Cardiovascular Magnetic Resonance
• 出版年：2011
• 出版时间：December 2011
• 年：2011
• 卷：13
• 期：1
• 全文大小：592KB
• 参考文献：1. Debette S, Leys D: Cervical-artery dissections: Predisposing factors, diagnosis, and outcome. / Lancet Neurol 2009, 8:668-78. CrossRef
  2. Georgiadis D, Arnold M, von Buedingen HC, Valko P, Sarikaya H, Rousson V, Mattle HP, Bousser MG, Baumgartner RW: Aspirin vs anticoagulation in carotid artery dissection: A study of 298 patients. / Neurology 2009, 72:1810-815. CrossRef
  3. Oppenheim C, Naggara O, Touze E, Lacour JC, Schmitt E, Bonneville F, Crozier S, Guegan-Massardier E, Gerardin E, Leclerc X, Neau JP, Sirol M, Toussaint JF, Mas JL, Meder JF: High-resolution mr imaging of the cervical arterial wall: What the radiologist needs to know. / Radiographics 2009, 29:1413-431. CrossRef
  4. Naggara O, Touze E, Marsico R, Leclerc X, Nguyen T, Mas JL, Pruvo JP, Meder JF, Oppenheim C: High-resolution mr imaging of periarterial edema associated with biological inflammation in spontaneous carotid dissection. / Eur Radiol 2009, 19:2255-260. CrossRef
  5. Bachmann R, Nassenstein I, Kooijman H, Dittrich R, Kugel H, Niederstadt T, Kuhlenbaumer G, Ringelstein EB, Kramer S, Heindel W: Spontaneous acute dissection of the internal carotid artery: High-resolution magnetic resonance imaging at 3.0 tesla with a dedicated surface coil. / Invest Radiol 2006, 41:105-11. CrossRef
  6. Schwartz NE, Vertinsky AT, Hirsch KG, Albers GW: Clinical and radiographic natural history of cervical artery dissections. / J Stroke Cerebrovasc Dis 2009, 18:416-23. CrossRef
  7. Schievink WI: Spontaneous dissection of the carotid and vertebral arteries. / N Engl J Med 2001, 344:898-06. CrossRef
  8. Gomori JM, Grossman RI: Mechanisms responsible for the mr appearance and evolution of intracranial hemorrhage. / Radiographics 1988, 8:427-40.
  9. Gomori JM, Grossman RI, Hackney DB, Goldberg HI, Zimmerman RA, Bilaniuk LT: Variable appearances of subacute intracranial hematomas on high-field spin-echo mr. / AJR Am J Roentgenol 1988, 150:171-78.
  10. Gomori JM, Grossman RI, Steiner I: High-field magnetic resonance imaging of intracranial hematomas. / Isr J Med Sci 1988, 24:218-23.
  11. Gomori JM, Grossman RI, Yu-Ip C, Asakura T: Nmr relaxation times of blood: Dependence on field strength, oxidation state, and cell integrity. / J Comput Assist Tomogr 1987, 11:684-90. CrossRef
  12. Lusby RJ, Ferrell LD, Ehrenfeld WK, Stoney RJ, Wylie EJ: Carotid plaque hemorrhage. Its role in production of cerebral ischemia. / Arch Surg 1982, 117:1479-488. CrossRef
  13. Chu B, Kampschulte A, Ferguson MS, Kerwin WS, Yarnykh VL, O'Brien KD, Polissar NL, Hatsukami TS, Yuan C: Hemorrhage in the atherosclerotic carotid plaque: A high-resolution mri study. / Stroke 2004, 35:1079-084. CrossRef
  14. Kwee RM, van Oostenbrugge RJ, Mess WH, Prins MH, van der Geest RJ, Ter Berg JW, Franke CL, Korten AG, Meems BJ, van Engelshoven JM, Wildberger JE, Kooi ME: Carotid plaques in transient ischemic attack and stroke patients: One-year follow-up study by magnetic resonance imaging. / Invest Radiol 2010.
  15. Saam T, Raya JG, Cyran CC, Bochmann K, Meimarakis G, Dietrich O, Clevert DA, Frey U, Yuan C, Hatsukami TS, Werf A, Reiser MF, Nikolaou K: High resolution carotid black-blood 3t mr with parallel imaging and dedicated 4-channel surface coils. / J Cardiovasc Magn Reson 2009, 11:41. CrossRef
  16. Saam T, Habs M, Cyran CC, Grimm J, Pfefferkorn T, Schuller U, Reiser MF, Nikolaou K: [new aspects of mri for diagnostics of large vessel vasculitis and primary angiitis of the central nervous system.]. / Radiologe 2010.
  17. Osborn AG, Salzman KL, Barkovich AJ: Diagnostic imaging. In / Brain. Salt Lake City, Utah: Amirsys; 2010.
  18. Dittrich R, Nassenstein I, Bachmann R, Maintz D, Nabavi DG, Heindel W, Kuhlenbaumer G, Ringelstein EB: Polyarterial clustered recurrence of cervical artery dissection seems to be the rule. / Neurology 2007, 69:180-86. CrossRef
  19. Takaya N, Yuan C, Chu B, Saam T, Polissar NL, Jarvik GP, Isaac C, McDonough J, Natiello C, Small R, Ferguson MS, Hatsukami TS: Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: A high-resolution magnetic resonance imaging study. / Circulation 2005, 111:2768-775. CrossRef
  20. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J: Atherosclerotic plaque progression and vulnerability to rupture: Angiogenesis as a source of intraplaque hemorrhage. / Arterioscler Thromb Vasc Biol 2005, 25:2054-061. CrossRef
  21. Arnold M, Kurmann R, Galimanis A, Sarikaya H, Stapf C, Gralla J, Georgiadis D, Fischer U, Mattle HP, Bousser MG, Baumgartner RW: Differences in demographic characteristics and risk factors in patients with spontaneous vertebral artery dissections with and without ischemic events. / Stroke 2010, 41:802-04. CrossRef
  22. Arnold M, Bousser MG, Fahrni G, Fischer U, Georgiadis D, Gandjour J, Benninger D, Sturzenegger M, Mattle HP, Baumgartner RW: Vertebral artery dissection: Presenting findings and predictors of outcome. / Stroke 2006, 37:2499-503. CrossRef
  23. Mokri B, Houser OW, Sandok BA, Piepgras DG: Spontaneous dissections of the vertebral arteries. / Neurology 1988, 38:880-85.
  24. Kirsch E, Kaim A, Engelter S, Lyrer P, Stock KW, Bongartz G, Radu EW: Mr angiography in internal carotid artery dissection: Improvement of diagnosis by selective demonstration of the intramural haematoma. / Neuroradiology 1998, 40:704-09. CrossRef
  25. Benninger DH, Georgiadis D, Kremer C, Studer A, Nedeltchev K, Baumgartner RW: Mechanism of ischemic infarct in spontaneous carotid dissection. / Stroke 2004, 35:482-85. CrossRef
  
• 作者单位：Maximilian Habs (1)
  Thomas Pfefferkorn (2)
  Clemens C Cyran (1)
  Jochen Grimm (1)
  Axel Rominger (3)
  Marcus Hacker (3)
  Christian Opherk (2)
  Maximilian F Reiser (1)
  Konstantin Nikolaou (1)
  Tobias Saam (1)
  
  1. Dept. of Clinical Radiology, University of Munich, Grosshadern Campus, Munich, Germany
  2. Dept. of Neurology, University of Munich, Grosshadern Campus, Munich, Germany
  3. Department of Nuclear Medicine, University of Munich, Grosshadern Campus, Munich, Germany
  

文摘

Background Previously proposed classifications for carotid plaque and cerebral parenchymal hemorrhages are used to estimate the age of hematoma according to its signal intensities on T1w and T2w MR images. Using these classifications, we systematically investigated the value of cardiovascular magnetic resonance (CMR) in determining the age of vessel wall hematoma (VWH) in patients with spontaneous cervical artery dissection (sCAD). Methods 35 consecutive patients (mean age 43.6 ± 9.8 years) with sCAD received a cervical multi-sequence 3T CMR with fat-saturated black-blood T1w-, T2w- and TOF images. Age of sCAD was defined as time between onset of symptoms (stroke, TIA or Horner's syndrome) and the CMR scan. VWH were categorized into hyperacute, acute, early subacute, late subacute and chronic based on their signal intensities on T1w- and T2w images. Results The mean age of sCAD was 2.0, 5.8, 15.7 and 58.7 days in patients with acute, early subacute, late subacute and chronic VWH as classified by CMR (p < 0.001 for trend). Agreement was moderate between VWH types in our study and the previously proposed time scheme of signal evolution for cerebral hemorrhage, Cohen's kappa 0.43 (p < 0.001). There was a strong agreement of CMR VWH classification compared to the time scheme which was proposed for carotid intraplaque hematomas with Cohen's kappa of 0.74 (p < 0.001). Conclusions Signal intensities of VWH in sCAD vary over time and multi-sequence CMR can help to determine the age of an arterial dissection. Furthermore, findings of this study suggest that the time course of carotid hematomas differs from that of cerebral hematomas.