Epidémie de méningite en République de Guinée en 2013 : émergence de Nesseria meningitidis W135

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• 作者：F. A. Traoré ; F. B. Sako ; D. Sylla…
• 关键词：Mots clésEpidémie ; Méningite ; Neisseria meningitidis W135 ; Siguiri ; Kankan ; Dabola ; Kintinian ; Guinée ; Afrique intertropicale
• 刊名：Bulletin de la Société de pathologie exotique
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：109
• 期：5
• 页码：364-367
• 全文大小：
• 刊物主题：Internal Medicine; Tropical Medicine; Infectious Diseases; Gastroenterology; Epidemiology; Parasitology;
• 出版者：Lavoisier
• ISSN：1961-9049
• 卷排序：109

文摘

A prospective study conducted from 1 January to 31 December 2013 described a meningitis epidemic in Republic of Guinea. The identification of the germs was based on Gram stain, latex agglutination and culture. During the study period, 480 suspected cases of meningitis were reported by 21 health districts. The average age was 18±8 years and 62.5% were men. The vaccination status was unknown in all patients. The largest attack rates were found in Siguiri (3.2 per 10,000), Kankan (2.6 per 10,000) and Dabola (3.9 per 10,000). The locality of Kintinian in Siguiri was the only one to cross the epidemic threshold. The identified microorganisms were Haemophilus influenzae (1 time), Pneumococcus (2 times), Neisseria meningitidis A (4 times) and W135 (10 times) with a total of 17 positive samples. All of these germs were sensitive to chloramphenicol, ceftriaxone and ciprofloxacin. The average hospital stay was 6.5±2 days. The lethality was 13.8%. This meningitis epidemic was characterized by the emergence of Neisseria meningitidis W135. The monitoring of this serogroup should be increased and future vaccination strategies must include it presence.