Production of medical ^99m Tc isotope via photonuclear reaction

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• 作者：M. Fujiwara ; K. Nakai ; N. Takahashi ; T. Hayakawa…
• 刊名：Physics of Particles and Nuclei
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：48
• 期：1
• 页码：124-133
• 全文大小：
• 刊物类别：Physics and Astronomy
• 刊物主题：Particle and Nuclear Physics;
• 出版者：Pleiades Publishing
• ISSN：1531-8559
• 卷排序：48

文摘

99mTc with a 6 hour half-life is one of the most important medical isotopes used for the Single-Photon Emission Computed Tomography (SPECT) inspection in hospitals of US, Canada, Europe and Japan. 99mTc isotopes are extracted by the milking method from parent 99Mo isotopes with a 66 hour half-life. The supply of 99Mo isotopes now encounters a serious crisis. Hospitals may not suitably receive 99Mo medical isotopes in near future, due to difficulties in production by research nuclear reactors. Many countries are now looking for alternative ways to generate 99Mo isotopes other than those with research reactors. We discuss a sustained availability of 99mTc isotopes via the natMo(γ, n) photonuclear reaction, and discuss to solve technical problems for extracting pure 99mTc isotopes from other output materials of photonuclear reactions.