- 作者:Jessica Tarleton ; Lisa Haddad…
- 关键词:Hormonal contraception ; HIV risk ; Progestins ; Vaginal microflora ; Vaginal microbiota ; Genital tract immune cells
- 刊名:Current Obstetrics and Gynecology Reports
- 出版年:2016
- 出版时间:March 2016
- 年:2016
- 卷:5
- 期:1
- 页码:20-29
- 全文大小:369 KB
- 参考文献:1.Wira CR, Rodriguez-Garcia M, Patel MV. The role of sex hormones in immune protection of the female reproductive tract. Nat Rev Immunol. 2015;15(4):217–30. doi:10.1038/nri3819 .PubMedCentral CrossRef PubMed
2.Murphy K, Irvin SC, Herold BC. Research gaps in defining the biological link between HIV risk and hormonal contraception. Am J Reprod Immunol. 2014;72(2):228–35. doi:10.1111/aji.12209 .PubMedCentral CrossRef PubMed
3.Beagley KW, Gockel CM. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol. 2003;38(1):13–22.CrossRef PubMed
4.Sonnex C. Influence of ovarian hormones on urogenital infection. Sex Transm Infect. 1998;74(1):11–9.PubMedCentral CrossRef PubMed
5.Martin Jr HL, Nyange PM, Richardson BA, Lavreys L, Mandaliya K, Jackson DJ, et al. Hormonal contraception, sexually transmitted diseases, and risk of heterosexual transmission of human immunodeficiency virus type 1. J Infect Dis. 1998;178(4):1053–9.CrossRef PubMed
6.Baeten JM, Nyange PM, Richardson BA, Lavreys L, Chohan B, Martin Jr HL, et al. Hormonal contraception and risk of sexually transmitted disease acquisition: results from a prospective study. Am J Obstet Gynecol. 2001;185(2):380–5. doi:10.1067/mob.2001.115862 .CrossRef PubMed
7.Polis CB, Phillips SJ, Curtis KM, Westreich DJ, Steyn PS, Raymond E, et al. Hormonal contraceptive methods and risk of HIV acquisition in women: a systematic review of epidemiological evidence. Contraception. 2014;90(4):360–90. doi:10.1016/j.contraception.2014.07.009 .CrossRef PubMed
8.Ralph LJ, McCoy SI, Shiu K, Padian NS. Hormonal contraceptive use and women’s risk of HIV acquisition: a meta-analysis of observational studies. Lancet Infect Dis. 2015;15(2):181–9. doi:10.1016/S1473-3099(14)71052-7 .PubMedCentral CrossRef PubMed
9.•
Noguchi LM, Richardson BA, Baeten JM, Hillier SL, Balkus JE, Chirenje ZM, et al. Risk of HIV-1 acquisition among women who use different types of injectable progestin contraception in South Africa: a prospective cohort study. Lancet HIV. 2015;2(7):e279–87. doi:10.1016/S2352-3018(15)00058-2 . Demonstrated lower risk of HIV-1 acquisition in women using NET-EN than DMPA.CrossRef PubMed
10.Morrison CS, Chen PL, Kwok C, Richardson BA, Chipato T, Mugerwa R, et al. Hormonal contraception and HIV acquisition: reanalysis using marginal structural modeling. AIDS. 2010;24(11):1778–81. doi:10.1097/QAD.0b013e32833a2537 .PubMedCentral CrossRef PubMed
11.Ward H, Ronn M. Contribution of sexually transmitted infections to the sexual transmission of HIV. Curr Opin HIV AIDS. 2010;5(4):305–10. doi:10.1097/COH.0b013e32833a8844 .PubMedCentral CrossRef PubMed
12.Witkin SS. The vaginal microbiome, vaginal anti-microbial defence mechanisms and the clinical challenge of reducing infection-related preterm birth. BJOG : Int J Obstet Gynaecol. 2015;122(2):213–8. doi:10.1111/1471-0528.13115 .CrossRef
13.Sirota I, Zarek SM, Segars JH. Potential influence of the microbiome on infertility and assisted reproductive technology. Semin Reprod Med. 2014;32(1):35–42. doi:10.1055/s-0033-1361821 .PubMedCentral CrossRef PubMed
14.van de Wijgert JH, Borgdorff H, Verhelst R, Crucitti T, Francis S, Verstraelen H, et al. The vaginal microbiota: what have we learned after a decade of molecular characterization? PLoS One. 2014;9(8), e105998. doi:10.1371/journal.pone.0105998 .PubMedCentral CrossRef PubMed
15.Brotman RM. Vaginal microbiome and sexually transmitted infections: an epidemiologic perspective. J Clin Invest. 2011;121(12):4610–7. doi:10.1172/JCI57172 .PubMedCentral CrossRef PubMed
16.Cone RA. Vaginal microbiota and sexually transmitted infections that may influence transmission of cell-associated HIV. J Infect Dis. 2014;210 Suppl 3:S616–21. doi:10.1093/infdis/jiu459 .PubMedCentral CrossRef PubMed
17.Hickey RJ, Zhou X, Pierson JD, Ravel J, Forney LJ. Understanding vaginal microbiome complexity from an ecological perspective. Transl Res : J Lab Clin Med. 2012;160(4):267–82. doi:10.1016/j.trsl.2012.02.008 .CrossRef
18.Boskey ER, Cone RA, Whaley KJ, Moench TR. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. Hum Reprod. 2001;16(9):1809–13.CrossRef PubMed
19.Boskey ER, Telsch KM, Whaley KJ, Moench TR, Cone RA. Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification. Infect Immun. 1999;67(10):5170–5.PubMedCentral PubMed
20.Mirmonsef P, Modur S, Burgad D, Gilbert D, Golub ET, French AL, et al. Exploratory comparison of vaginal glycogen and Lactobacillus levels in premenopausal and postmenopausal women. Menopause. 2015;22(7):702–9. doi:10.1097/GME.0000000000000397 .CrossRef PubMed
21.Jespers V, Menten J, Smet H, Poradosu S, Abdellati S, Verhelst R, et al. Quantification of bacterial species of the vaginal microbiome in different groups of women, using nucleic acid amplification tests. BMC Microbiol. 2012;12:83. doi:10.1186/1471-2180-12-83 .PubMedCentral CrossRef PubMed
22.Srinivasan S, Liu C, Mitchell CM, Fiedler TL, Thomas KK, Agnew KJ, et al. Temporal variability of human vaginal bacteria and relationship with bacterial vaginosis. PLoS One. 2010;5(4), e10197. doi:10.1371/journal.pone.0010197 .PubMedCentral CrossRef PubMed
23.Brotman RM, Shardell MD, Gajer P, Tracy JK, Zenilman JM, Ravel J, et al. Interplay between the temporal dynamics of the vaginal microbiota and human papillomavirus detection. J Infect Dis. 2014;210(11):1723–33. doi:10.1093/infdis/jiu330 .PubMedCentral CrossRef PubMed
24.Bradshaw CS, Vodstrcil LA, Hocking JS, Law M, Pirotta M, Garland SM, et al. Recurrence of bacterial vaginosis is significantly associated with posttreatment sexual activities and hormonal contraceptive use. Clin Infect Dis. 2013;56(6):777–86. doi:10.1093/cid/cis1030 .CrossRef PubMed
25.Calzolari E, Masciangelo R, Milite V, Verteramo R. Bacterial vaginosis and contraceptive methods. Int J Gynecol Obstet. 2000;70(3):341–6. doi:10.1016/s0020-7292(00)00217-4 .CrossRef
26.Rifkin SB, Smith MR, Brotman RM, Gindi RM, Erbelding EJ. Hormonal contraception and risk of bacterial vaginosis diagnosis in an observational study of women attending STD clinics in Baltimore. MD Contracept. 2009;80(1):63–7. doi:10.1016/j.contraception.2009.01.008 .CrossRef
27.Holzman C, Leventhal JM, Qiu H, Jones NM, Wang J, Grp BVS. Factors linked to bacterial vaginosis in nonpregnant women. Am J Public Health. 2001;91(10):1664–70. doi:10.2105/ajph.91.10.1664 .PubMedCentral CrossRef PubMed
28.Riggs M, Klebanoff M, Nansel T, Zhang J, Schwebke J, Andrews W. Longitudinal association between hormonal contraceptives and bacterial vaginosis in women of reproductive age. Sex Transm Dis. 2007;34(12):954–9. doi:10.1097/OLQ.0b013e31811ed0e4 .PubMed
29.Mitchell CM, McLemore L, Westerberg K, Astronomo R, Smythe K, Gardella C, et al. Long-term effect of depot medroxyprogesterone acetate on vaginal microbiota, epithelial thickness and HIV target cells. J Infect Dis. 2014;210(4):651–5. doi:10.1093/infdis/jiu176 .PubMedCentral CrossRef PubMed
30.Shoubnikova M, Hellberg D, Nilsson S, Mardh PA. Contraceptive use in women with bacterial vaginosis. Contraception. 1997;55(6):355–8. doi:10.1016/s0010-7824(97)00044-9 .CrossRef PubMed
31.Madden T, Grentzer JM, Secura GM, Allsworth JE, Peipert JF. Risk of bacterial vaginosis in users of the intrauterine device: a longitudinal study. Sex Transm Dis. 2012;39(3):217–22. doi:10.1097/OLQ.0b013e31823e68fe .PubMedCentral CrossRef PubMed
32.Jacobson JC, Turok DK, Dermish AI, Nygaard IE, Settles ML. Vaginal microbiome changes with levonorgestrel intrauterine system placement. Contraception. 2014;90(2):130–5. doi:10.1016/j.contraception.2014.04.006 .CrossRef PubMed
33.Veres S, Miller L, Burington B. A comparison between the vaginal ring and oral contraceptives. Obstet Gynecol. 2004;104(3):555–63. doi:10.1097/01.AOG.0000136082.59644.13 .CrossRef PubMed
34.De Seta F, Restaino S, De Santo D, Stabile G, Banco R, Busetti M, et al. Effects of hormonal contraception on vaginal flora. Contraception. 2012;86(5):526–9. doi:10.1016/j.contraception.2012.02.012 .CrossRef PubMed
35.Gunawardana M, Moss JA, Smith TJ, Kennedy S, Kopin E, Nguyen C, et al. Microbial biofilms on the surface of intravaginal rings worn in non-human primates. J Med Microbiol. 2011;60(Pt 6):828–37. doi:10.1099/jmm.0.028225-0 .PubMedCentral CrossRef PubMed
36.Huang Y, Merkatz RB, Hillier SL, Roberts K, Blithe DL, Sitruk-Ware R, et al. Effects of a one year reusable contraceptive vaginal ring on vaginal microflora and the risk of vaginal infection: an open-label prospective evaluation. PLoS One. 2015;10(8), e0134460. doi:10.1371/journal.pone.0134460 .PubMedCentral CrossRef PubMed
37.•
van de Wijgert JH, Verwijs MC, Turner AN, Morrison CS. Hormonal contraception decreases bacterial vaginosis but oral contraception may increase candidiasis: implications for HIV transmission. AIDS. 2013;27(13):2141–53. doi:10.1097/QAD.0b013e32836290b6 . This meta-analysis of 36 studies estimated a 10–20% reduction in BV in combined oral contraceptive uses and 18–30% reduction in BV in DMPA users.CrossRef PubMed