Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer
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- 作者：Wendy Demark-Wahnefried ; Jeffery W. Nix ; Gary R. Hunter ; Soroush Rais-Bahrami…
- 关键词：Prostatic neoplasms ; Diet ; Physical activity ; Exercise ; Weight loss ; Obesity ; Intervention ; Presurgical
- 刊名：BMC Cancer
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：16
- 期：1
- 全文大小：630 KB
- 参考文献：1.Ligibel JA, Alfano CM, Courneya KS, Demark-Wahnefried W, Burger RA, Chlebowski RT, et al. American society of clinical oncology position statement on obesity and cancer. J Clin Oncol. 2014;32(31):3568–74.CrossRef PubMed
2.Zhao ZG, Guo XG, Ba CX, Woang W, Yang YY, Wang J, et al. Overweight, obesity and thyroid cancer risk: a meta-analysis of cohort studies. J Intl Med Res. 2012;40(6):2041–50.CrossRef
3.Larsson SC, Wolk A. Obesity and the risk of gallbladder cancer: a meta-analysis. Br J Cancer. 2007;96(9):1457–61.PubMedCentral PubMed
4.Demark-Wahnefried W, Platz EA, Ligibel JA, Blair CK, Courneya KS, Meyerhardt JA, et al. The role of obesity in cancer survival and recurrence. Cancer Epidemiol Biomarkers Prev. 2012;21(8):1244–59.PubMedCentral CrossRef PubMed
5.Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. New Engl J Med. 2003;348(17):1625–38.CrossRef PubMed
6.Magheli A, Rais-Bahrami S, Trock BJ, Humphreys EB, Partin AW, Han M, et al. Impact of body mass index on biochemical recurrence rates after radical prostatectomy: an analysis utilizing propensity score matching. Urol. 2008;72(6):1246–51.PubMedCentral CrossRef PubMed
7.Yuan C, Cao Y, Chavarro J, Lindstrom S, Qiu W, Willett W, et al. Prediagnostic body-mass index, smoking and prostate cancer survival: a cohort consortium study of over 10,000 white men with prostate cancer. Cancer Epidemiol Biomarkers Prev. 2015;24(4):759–60.CrossRef
8.Cao Y, Ma J. Body mass index, prostate cancer-specific mortality, and biochemical recurrence: a systematic review and meta-analysis. Cancer Prev Res. 2011;4(4):486–501.CrossRef
9.Reeves MM, Terranova CO, Eakin EG, Demark-Wahnefried W. Weight loss intervention trials in women with breast cancer: a systematic review. Obesity Rev. 2014;15(9):749–68.CrossRef
10.Befort CA, Klemp JR, Austin HL, Perri MG, Schmitz KH, Sullivan DK, et al. Outcomes of a weight loss intervention among rural breast cancer survivors. Breast Cancer Res Treat. 2012;132(2):631–9.PubMedCentral CrossRef PubMed
11.Thomson CA, Stopeck AT, Bea JW, Cussler E, Nardi E, Frey G, et al. Changes in body weight and metabolic indexes in overweight breast cancer survivors enrolled in a randomized trial of low-fat vs. reduced carbohydrate diets. Nutr Cancer. 2010;62(8):1142–52.CrossRef PubMed
12.Campbell KL, Van Patten CL, Neil SE, Kirkham AA, Gotay CC, Gelmon KA, et al. Feasibility of a lifestyle intervention on body weight and serum biomarkers in breast cancer survivors with overweight and obesity. J Acad Nutr Diet. 2012;112(4):559–67.CrossRef PubMed
13.Greenlee HA, Crew KD, Mata JM, McKinley PS, Rundle AG, Zhang W, et al. A pilot randomized controlled trial of a commercial diet and exercise weight loss program in minority breast cancer survivors. Obes. 2013;21(1):65–76.CrossRef
14.Jen KL, Djuric Z, DiLaura NM, Buison A, Redd JN, Maranci V, et al. Improvement of metabolism among obese breast cancer survivors in differing weight loss regimens. Obesity Res. 2004;12(2):306–12.CrossRef
15.Scott E, Daley AJ, Doll H, Woodroofe N, Coleman RE, Mutrie N, et al. Effects of an exercise and hypocaloric healthy eating program on biomarkers associated with long-term prognosis after early-stage breast cancer: a randomized controlled trial. Cancer Causes Contr. 2013;24(1):181–91.CrossRef
16.Rack B, Andergassen U, Neugebauer J, Salmen J, Hepp P, Sommer H, et al. The German SUCCESS C study - the first European lifestyle study on breast cancer. Breast Care. 2010;5(6):395–400.PubMedCentral CrossRef PubMed
17.Villarini A, Pasanisi P, Traina A, Mano MP, Bonanni B, Panico S, et al. Lifestyle and breast cancer recurrences: the DIANA-5 trial. Tumori. 2012;98(1):1–18.PubMed
18.Morey MC, Snyder DC, Sloane R, Cohen HJ, Peterson B, Hartman TJ, et al. Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial. JAMA. 2009;301(18):1883–91.PubMedCentral CrossRef PubMed
19.Schenk JM, Neuhouser ML, Lin DW, Kristal AR. A dietary intervention to elicit rapid and complex dietary changes for studies investigating the effects of diet on tissues collected during invasive surgical procedures. J Am Diet Assn. 2009;109(3):459–63.CrossRef
20.Wright JL, Plymate S, D’Oria-Cameron A, Bain C, Haugk K, Xiao L, et al. A study of caloric restriction versus standard diet in overweight men with newly diagnosed prostate cancer: a randomized controlled trial. Prostate. 2013;73(12):1345–51.PubMedCentral CrossRef PubMed
21.Demark-Wahnefried W, Polascik TJ, George SL, Switzer BR, Madden JF, Ruffin MT, et al. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. Cancer Epidemiol Biomarkers Prev. 2008;17(12):3577–87.PubMedCentral CrossRef PubMed
22.DeCensi A, Puntoni M, Gandini S, Guerrieri-Gonzaga A, Johansson HA, Cazzaniga M, et al. Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial. Breast Cancer Res Treat. 2014;148(1):81–90.PubMedCentral CrossRef PubMed
23.Gandini S, Guerrieri-Gonzaga A, Pruneri G, Serrano D, Cazzaniga M, Lazzeroni M, et al. Association of molecular subtypes with Ki-67 changes in untreated breast cancer patients undergoing pre-surgical trials. Ann Oncol. 2014;25(3):618–23.PubMedCentral CrossRef PubMed
24.Kelloff GJ, Boone CW, Steele VE, Crowell JA, Lubet R, Sigman CC. Progress in cancer chemoprevention: perspectives on agent selection and short-term clinical intervention trials. Cancer Res. 1994;54(7 Suppl):2015s–24.PubMed
25.Arnaout A, Robertson S, Kuchuk I, Simos D, Pond GR, Addison CL, et al. Evaluating the feasibility of performing window of opportunity trials in breast cancer. Int J Surg Oncol. 2015;2015:785793.PubMedCentral PubMed
26.Dinney CP, Hansel D, McConkey D, Shipley W, Hagan M, Dreicer R, et al. Novel neoadjuvant therapy paradigms for bladder cancer: results from the National Cancer Center Institute Forum. Urol Oncol. 2014;32(8):1108–15.PubMedCentral CrossRef PubMed
27.Dowsett M, Smith I, Robertson J, Robison L, Pinhel I, Johnson L, et al. Endocrine therapy, new biologicals, and new study designs for presurgical studies in breast cancer. J Natl Cancer Inst Monogr. 2011;2011(43):120–3.CrossRef PubMed
28.Montironi R, Bartels PH, DeCensi A, Puntoni M, Hurle R, Decobelli O, et al. A randomized phase IIb presurgical study of finasteride vs. low-dose flutamide vs. placebo in men with prostate cancer. Efficacy monitored by karyometry. Urol Oncol. 2013;31(5):557–65.CrossRef PubMed
29.Demark-Wahnefried W, George SL, Switzer BR, Snyder DC, Madden JF, Polascik TJ, et al. Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer. Clin Trials. 2008;5(3):262–72.PubMedCentral CrossRef PubMed
30.Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, et al. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Science Sports Exerc. 2010;42(7):1409–26.CrossRef
31.Segal RJ, Reid RD, Courneya KS, Sigal RJ, Kenny GP, Prud’Homme DG, et al. Randomized controlled trial of resistance or aerobic exercise in men receiving radiation therapy for prostate cancer. J Clin Oncol. 2009;27(3):344–51.CrossRef PubMed
32.Jayachandran J, Banez LL, Aronson WJ, Terris MK, Presti Jr JC, Amling CL, et al. Obesity as a predictor of adverse outcome across black and white race: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) Database. Cancer. 2009;115(22):5263–71.PubMedCentral CrossRef PubMed
33.Hadziabdic MO, Mucalo I, Hrabac P, Matic T, Rahelic D, Bozikov V. Factors predictive of drop-out and weight loss success in weight management of obese patients. J Hum Nutr Diet. 2015;28 Suppl 2:24–32.CrossRef PubMed
34.World Cancer Research Fund/American Institute of Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective, second expert report. [http://www.dietandcancerreport.org/expert_report/ ]. Accessed 3 Feb 2016.
35.Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin. 2012;62(4):243–74.CrossRef PubMed
36.Frankenfield DC, Rowe WA, Smith JS, Cooney RN. Validation of several established equations for resting metabolic rate in obese and nonobese people. J Am Diet Assn. 2003;103(9):1152–9.CrossRef
37.Choose Your Foods Exchange List Diet. [http://glycemic.com/DiabeticExchange/The%20Diabetic%20Exchange%20List.pdf ]. Accessed 3 Feb 2016.
38.Steinberg DM, Bennett GG, Askew S, Tate DF. Weighing every day matters: daily weighing improves weight loss and adoption of weight control behaviors. J Acad Nutr Diet. 2015;115(4):511–8.CrossRef PubMed
39.Bandura A. Health promotion by social cognitive means. Health Ed Behav. 2004;31(2):143–64.CrossRef
40.Kohl HW, Gibbons LW, Gordon NF, Blair SN. An empirical evaluation of the ACSM guidelines for exercise testing. Med Science Sports Exerc. 1990;22(4):533–9.CrossRef
41.Lohman TG, Roche AF, Martorell R. Anthropometric Standardization Reference Manual. Champaign: Human Kinetics Books; 1988.
42.Fillenbaum G. Multidimensional Functional Assessment of Older Adults. Hillsdale: Lawrence Erlbaum Associates; 1988.
43.Hays RD, Sherbourne CD, Mazel RM. The RAND 36-Item Health Survey 1.0. Health Econ. 1993;2(3):217–27.CrossRef PubMed
44.Litwin MS, Hays RD, Fink A, Ganz PA, Leake B, Brook RH. The UCLA Prostate Cancer Index: development, reliability, and validity of a health-related quality of life measure. Med Care. 1998;36(7):1002–12.CrossRef PubMed
45.Blair SN, Haskell WL, Ho P, Paffenbarger Jr RS, Vranizan KM, Farquhar JW, et al. Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments. Am J Epidemiol. 1985;122(5):794–804.PubMed
46.De Keyzer W, Huybrechts I, De Vriendt V, Vandevijvere S, Slimani N, Van Oyen H, et al. Repeated 24-h recalls versus dietary records for estimating nutrient intakes in a national food consumption survey. Food Nutr Res 2011;55. doi: 10.3402/fnr.v55i0.7307
47.Subar AF, Kirkpatrick SI, Mittl B, Zimmerman TP, Thompson FE, Bingley C, et al. The Automated Self-Administered 24-h Dietary Recall (ASA24): A Resource for Researchers, Clinicians and Educators from the National Cancer Institute. J Acad Nutr Diet. 2012;112(8):1134–7.PubMedCentral CrossRef PubMed
48.Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, et al. Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest. 2013;93(6):690–700.PubMedCentral CrossRef PubMed
49.Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM. Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets. J Vis Exp 2014(85). doi:10.3791/51301
50.Kumar R, Eipers P, Little RB, Crowley M, Crossman DK, Lefkowitz EJ, et al. Getting started with microbiome analysis: sample acquisition to bioinformatics. Curr Protoc Hum Genet. 2014;82:11–8. 18, 29.
51.Daft JG, Ptacek T, Kumar R, Morrow C, Lorenz RG. Cross-fostering immediately after birth induces a permanent microbiota shift that is shaped by the nursing mother. Microbiome. 2015;3:17.PubMedCentral CrossRef PubMed
52.Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Lozupone CA, Turnbaugh PJ, et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci U S A. 2011;108 Suppl 1:4516–22.PubMedCentral CrossRef PubMed
53.Adams RN, Mosher CE, Blair CK, Snyder DC, Sloane R, Demark-Wahnefried W. Cancer survivors’ uptake and adherence in diet and exercise intervention trials: An integrative data analysis. Cancer. 2014;121(1):77–83.PubMedCentral CrossRef PubMed - 作者单位：Wendy Demark-Wahnefried (1)
Jeffery W. Nix (2)
Gary R. Hunter (3)
Soroush Rais-Bahrami (2)
Renee A. Desmond (4)
Balu Chacko (5)
Casey D. Morrow (6)
Maria Azrad (1)
Andrew D. Frugé (1)
Yuko Tsuruta (1)
Travis Ptacek (7)
Scott A. Tully (8)
Roanne Segal (9)
William E. Grizzle (10)
1. Department of Nutrition Sciences, University of Alabama at Birmingham (UAB), 346 Webb Nutrition Sciences Bldg., 1675 University Blvd, Birmingham, AL, USA
2. Department of Urology, UAB, Birmingham, AL, USA
3. Department of Human Studies, UAB, Birmingham, AL, USA
4. Department of Preventive Medicine, UAB, Birmingham, AL, USA
5. Department of Molecular & Cellular Pathology, UAB, Birmingham, AL, USA
6. Department of Cell, Developmental & Integrative Biology, UAB, Birmingham, AL, USA
7. Department of Microbiology, UAB, Birmingham, AL, USA
8. Urology Centers of Alabama, Birmingham, AL, USA
9. Department of Medicine, University of Ottawa, Ontario, Canada
10. Department of Pathology, UAB, Birmingham, AL, USA - 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2407
文摘
Background Obesity is associated with tumor aggressiveness and disease-specific mortality for more than 15 defined malignancies, including prostate cancer. Preclinical studies suggest that weight loss from caloric restriction and increased physical activity may suppress hormonal, energy-sensing, and inflammatory factors that drive neoplastic progression; however, exact mechanisms are yet to be determined, and experiments in humans are limited.