Quantitative motor assessment of muscular weakness in myasthenia gravis: a pilot study
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- 作者：Sarah Hoffmann ; Jana Siedler ; Alexander U. Brandt ; Sophie K. Piper…
- 关键词：Myasthenia gravis ; Neurophysiology ; Case control studies ; Diagnostic tests ; Clinical trial
- 刊名：BMC Neurology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：15
- 期：1
- 全文大小：686 KB
- 刊物主题：Neurology; Neurochemistry; Neurosurgery;
- 出版者：BioMed Central
- ISSN：1471-2377
文摘
Background Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles. We hypothesized that muscular weakness in patients with MG can be quantified with the non-invasive Quantitative Motor (Q-Motor) test for Grip Force Assessment (QGFA) and Involuntary Movement Assessment (QIMA) and that pathological findings correlate with disease severity as measured by QMG.