Effect of LED-mediated-photobiomodulation therapy on orthodontic tooth movement and root resorption in rats

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• 作者：Abdullah Ekizer ; Tancan Uysal ; Enis Güray ; Derya Akku?
• 关键词：Low ; level laser therapy ; Tooth movement ; Orthodontics ; Rats
• 刊名：Lasers in Medical Science
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：30
• 期：2
• 页码：779-785
• 全文大小：576 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Medicine/Public Health, general
  Dentistry
  Laser Technology and Physics and Photonics
  Quantum Optics, Quantum Electronics and Nonlinear Optics
  Applied Optics, Optoelectronics and Optical Devices
  
• 出版者：Springer London
• ISSN：1435-604X

文摘

The aim of this experimental study was to evaluate the effects of light-emitting diode-mediated-photobiomodulation therapy (LPT), on the rate of orthodontic tooth movement (TM) and orthodontically induced root resorption, in rats. Twenty male 12-week-old Wistar rats were separated into two groups (control and LPT) and 50?cN of force was applied between maxillary left molar and incisor with a coil spring. In the treatment group, LPT was applied with an energy density of 20?mW/cm2 over a period of 10 consecutive days directly over the movement of the first molar teeth area. The distance between the teeth was measured with a digital caliper on days?0 (T0), 10 (T1), and 21 (T2) on dental cast models. The surface area of root resorption lacunae was measured histomorphometrically using digital photomicrographs. Mann–Whitney U and Wilcoxon tests were used for statistical evaluation at p--.05 level. TM during two different time intervals (T1–T0 and T2–T1) were compared for both groups and a statistically significant difference was found in the LPT group (p--.016). The TM amount at the first time period (1.31?±-.36?mm) was significantly higher than the second time period (0.24?±-.23?mm) in the LPT group. Statistical analysis showed significant differences between two groups after treatment/observation period (p--.017). The magnitude of movement in the treatment group was higher (1.55?±-.33?mm) compared to the control group (1.06?±-.35?mm). Histomorphometric analysis of root resorption, expressed as a percentage, showed that the average relative root resorption affecting the maxillary molars on the TM side was 0.098?±-.066 in the LPT group and 0.494?±-.224 in the control group. Statistically significant inhibition of root resorption with LPT was determined (p--.001) on the TM side. The LPT method has the potential of accelerating orthodontic tooth movement and inhibitory effects on orthodontically induced resorptive activity.