Steroid for chronic subdural hematoma? A prospective phase IIB pilot randomized controlled trial on the use of dexamethasone with surgical drainage for the reduction of recurrence with reoperation

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• 作者：David Yuen Chung Chan ; Tin Fung David Sun ; Wai Sang Poon
• 关键词：Chronic subdural hematoma ; Steroid ; Burr hole for drainage
• 刊名：Chinese Neurosurgical Journal
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：1
• 期：1
• 全文大小：409KB
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• 作者单位：David Yuen Chung Chan (1)
  Tin Fung David Sun (1)
  Wai Sang Poon (1)
  
  1. Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, 30-32 Ngan Shing Street, Shatin, NT, Hong Kong
  
• 刊物类别：Neurosurgery;
• 刊物主题：Neurosurgery;
• 出版者：BioMed Central
• ISSN：2057-4967

文摘

Background Chronic subdural hematoma is a common neurosurgical condition especially in the aging population. Burr hole for drainage is an effective treatment, yet recurrence is reported at 8 to 22 % worldwide, and 1-year mortality rates could be as high as 32 %. Our previous study on the use of dexamethasone as a primary nonsurgical treatment showed good response in selected group of patients. This study aims to assess the efficacy of dexamethasone with surgical drainage in the reduction of recurrence requiring reoperation.