Robust free-breathing SASHA T₁ mapping with high-contrast image registration

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• 作者：Kelvin Chow ; Yang Yang ; Peter Shaw…
• 关键词：T1 mapping ; SASHA ; Free ; breathing ; Image registration ; Extracellular volume ; Fibrosis
• 刊名：Journal of Cardiovascular Magnetic Resonance
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：18
• 期：1
• 全文大小：3,198 KB
• 刊物主题：Imaging / Radiology; Angiology; Cardiology;
• 出版者：BioMed Central
• ISSN：1532-429X
• 卷排序：18

文摘

BackgroundMany widely used myocardial T₁ mapping sequences use breath-hold acquisitions that limit the precision of calculated T₁ maps. The SAturation-recovery single-SHot Acquisition (SASHA) sequence has high accuracy with robustness against systematic confounders, but has poorer precision compared to the commonly used MOdified Look-Locker Inversion recovery (MOLLI) sequence. We propose a novel method for generating high-contrast SASHA images to enable a robust image registration approach to free-breathing T₁ mapping with high accuracy and precision.