Role of autologous platelet-rich plasma in treatment of long-bone nonunions: a prospective study

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• 作者：R. Malhotra ; V. Kumar ; B. Garg ; R. Singh ; V. Jain ; P. Coshic&#8230
• 关键词：Nonunion ; Platelet ; rich plasma (PRP) ; Femur ; Tibia ; Humerus ; Radius
• 刊名：MUSCULOSKELETAL SURGERY
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：99
• 期：3
• 页码：243-248
• 全文大小：585 KB
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• 作者单位：R. Malhotra (1)
  V. Kumar (1)
  B. Garg (1)
  R. Singh (1)
  V. Jain (1)
  P. Coshic (2)
  K. Chatterjee (2)
  
  1. Department of Orthopedics, All India Institute of Medical Sciences, New Delhi, 110029, India
  2. Department of Transfusion Medicine, AIIMS, New Delhi, India
  
• 刊物主题：Orthopedics; Surgical Orthopedics;
• 出版者：Springer Milan
• ISSN：2035-5114

文摘

Purpose Fracture union is a complex biological process, which depends upon several systemic and local factors. Disturbance of any of these factors may lead to nonunion of the fracture. These nonunions have a huge impact on quality of life as well as socioeconomical aspects. The platelets on activation release a number of growth factors and differentiation factors, which play important role in fracture healing. This study aimed to look for efficacy of platelet-rich plasma in the treatment of established fracture nonunions of long bones.