Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE−/− mice
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- 作者：C. Perez-Ternero ; M. D. Herrera ; U. Laufs…
- 关键词：ApoE−/−Rice bran enzymatic extract ; Atherosclerosis ; Inflammation ; Apoptosis ; Telomeres
- 刊名：European Journal of Nutrition
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：56
- 期：1
- 页码：225-236
- 全文大小：
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Nutrition;
- 出版者：Springer Berlin Heidelberg
- ISSN：1435-1293
- 卷排序：56
文摘
PurposeAtherosclerosis is associated with reduced mononuclear cell (MNC) telomere length, and senescent cells have been detected in atherosclerotic plaques. Rice bran is a source of γ-oryzanol, phytosterols and tocols with potential lipid-lowering, antioxidant and anti-inflammatory activities. Here, we tested the hypothesis that rice bran enzymatic extract (RBEE) impacts on apoptosis, telomere length and atherogenesis in mice.