Changes in resting mitogen-activated protein kinases following resistance exercise overreaching and overtraining

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• 作者：Justin X. Nicoll ; Andrew C. Fry ; Andrew J. Galpin…
• 关键词：Muscle ; Signaling ; Signal transduction ; High ; intensity exercise ; High ; power exercise ; Stressful exercise
• 刊名：European Journal of Applied Physiology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：116
• 期：11-12
• 页码：2401-2413
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Human Physiology; Occupational Medicine/Industrial Medicine; Sports Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1439-6327
• 卷排序：116

文摘

PurposeMany physiological maladaptations persist after overreaching and overtraining resistance exercise (RE). However, no studies have investigated changes in mitogen-activated protein kinases (MAPK) after overtraining in humans, despite their critical role regulating exercise-induced muscular adaptations. The purpose of this study was to describe the changes in total and resting phosphorylation status of extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun NH₂-terminal kinase (JNK) and p38-MAPK following a period of RE overreaching or overtraining.