参考文献:1.Whitcup SM, Nussenblatt RB. Immunologic mechanisms of uveitis. New targets for immunomodulation. Arch Ophthalmol 1997;115:520–525.CrossRef PubMed 2.Rothova A, Suttorp VS, Frits T, Kijlstra A. Causes and frequency of blindness in patients with intraocular inflammatory disease. Br J Ophthalmol 1996;80:332–336.PubMedCentral CrossRef PubMed 3.Huang M, Hao YL, Chen MR, Xie XF. Preparation and quality control of Yanyankang San. Chin J Hospit Pharm (Chin) 2010;30:1714–1716. 4.The Ministry of Science and Technology of the People's Republic of China. Guidance suggestions for the care and use of laboratory animals. 2006-9-30. 5.Jia XZ, Hu MH, Wang CH, Wang CY, Zhang FY, Han QL, et al. Coordinated gene expression of Th17- and Tregassociated molecules correlated with resolution of the monophasic experimental autoimmune uveitis. Molecular Vision 2011;17:1493–1507.PubMedCentral PubMed 6.Agarwal RK, Caspi RR. Rodent models of experimental autoimmune uveitis. Methods Mol Med 2004;102:395–419.PubMed 7.Aibara M, Lindsey JD, Weinreb RN. Reduction of intraocular pressure in mouse eyes treated with latanoprost. Invest Ophthalmol Vis Sci 2002;43;146–150. 8.Caspi RR. Th1 and Th2 responses in pathogenesis and regulation of experimental autoimmune uveoretinitis. Int Rev Immunol 2002;21:197–208.CrossRef PubMed 9.Crane IJ, Xu HP, Wallace C, Manivannan A, Mack M, Liversidge J, et al. Involvement of CCR5 in the passage of Th1-type cells across the blood-retina barrier in experimental autoimmune uveitis. J Leukoc Biol 2006;79:435–443.CrossRef PubMed 10.Tarrant TK, Silver PB, Chan CC, Wiggert B, Caspi RR. Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis. Immunol 1998;161:122–127. 11.Sun B, Sun SH, Chan CC, Wiggert C, Caspi RR. Autoimmunity to a pathogenic retinal antigen begins as a balanced cytokine response that polarizes towards type 1 in a disease-susceptible and towards type 2 in a diseaseresistant genotype. Int Immunol 1999;11:1307–1312.CrossRef PubMed 12.Mosmann TR. Properties and functions of interleukin-10. Adv Immunol 1994;56:1–26.CrossRef PubMed 13.Ishida H, Dobashi H. Interleukin-7, 8, 9, 10. Nihon Rinsho 2010;68:78–81.PubMed 14.Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Paola RD, Genovese T, et al. Absence of endogeneous interleukin-10 enhances the evolution of acute lung injury. Eur Cytokine Net 2002;13:285–297. 15.Lee YS, Ahjoku AO, Yu CR, Egwuagu CE. Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10. Immunology 2011;132:492–502.PubMedCentral CrossRef PubMed 16.Rizzo LV, Xu H, Chan CC, Wiggert B, Caspi RR. IL-10 has a protective role in experimental autoimmune uveoretinitis. Int Immunol 1998;10:807–814.CrossRef PubMed
1. Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250002, China 3. Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, China 2. Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan, 250002, China
刊物主题:Medicine/Public Health, general;
出版者:Springer Berlin Heidelberg
ISSN:1993-0402
文摘
Objective To study the influence of Yanyankang Powder (眼炎康散) on Th1/Th2 in rats with experimental autoimmune uveitis (EAU).