What is the ideal dose and power output of low-level laser therapy (810 nm) on muscle performance and post-exercise recovery? Study protocol for a double-blind, randomized, placebo-controlled trial

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• 作者：Adriano Rodrigues de Oliveira (5)
  Adriane Aver Vanin (6)
  Thiago De Marchi (5)
  Fernanda Colella Antonialli (6)
  Vanessa dos Santos Grandinetti (5)
  Paulo Roberto Vicente de Paiva (5)
  Gianna Móes Albuquerque Pontes (5)
  Larissa Aline Santos (6)
  Ivo de Oliveira Aleixo Junior (6)
  Paulo de Tarso Camillo de Carvalho (5) (6)
  Jan Magnus Bjordal (6)
  Ernesto Cesar Pinto Leal-Junior (5) (6)
  
• 关键词：Low ; level laser therapy ; Skeletal muscle fatigue ; Skeletal muscle recovery ; Phototherapy parameters ; Exercise
• 刊名：Trials
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：15
• 期：1
• 全文大小：316 KB
• 参考文献：1. Chalder T, Berelowitz G, Pawlikowska T, Watts L, Wessely S, Wright D, Wallace EP: Development of a fatigue scale. / J Psychosom Res 1993, 37:147-53. CrossRef
  2. Kawakami Y, Amemiya K, Kanehisa H, Ikegawa S, Fukunaga T: Fatigue responses of human triceps surae muscles during repetitive maximal isometric contractions. / J. Appl. Physiol 1969-975, 2000:88.
  3. Pasquet B, Carpentier A, Duchateau J, Hainaut K: Muscle fatigue during concentric and eccentric contractions. / Muscle Nerve 2000, 23:1727-735. CrossRef
  4. Torisu T, Wang K, Svensson P, De Laat A, Fujii H, Arendt-Nielsen L: Effects of muscle fatigue induced by low-level clenching on experimental muscle pain and resting jaw muscle activity: gender differences. / Exp. Brain Res 2006, 174:566-74. CrossRef
  5. Totsuka M, Nakaji S, Suzuki K, Sugawara K, Sato K: Break point of serum creatine kinase release after endurance exercise. / J Appl Physiol 2002, 93:1280-286.
  6. Proske U, Morgan DL: Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. / J Physiol 2001,537(2):333-45. CrossRef
  7. Morgan DL, Allen DG: Early events in stretch-induced muscle damage. / J Appl Physiol 2007-015, 1999:87.
  8. Byrne C, Twist C, Eston R: Neuromuscular function after exercise-induced muscle damage—theoretical and applied implications. / Sports Med 2004, 34:49-9. CrossRef
  9. Clarkson PM, Hubal MJ: Exercise-induced muscle damage. / Am J Phys Med Rehabil 2002, 81:S52-S69. CrossRef
  10. Cheung K, Hume P, Maxwell L: Delayed onset muscle soreness: treatment strategies and performance factors. / Sports Med 2003, 33:145-64. CrossRef
  11. Howatson G, van Someren KA: The prevention and treatment of exercise-induced muscle damage. / Sports Med 2008, 38:483-50. CrossRef
  12. Barnett A: Using recovery modalities between training sessions in elite athletes: does it help? / Sports Med 2006, 36:781-96. CrossRef
  13. Ahmaidi S, Granier P, Taoutaou Z, Mercier J, Dubouchaud H, Prefaut C: Effects of active recovery on plasma lactate and anaerobic power following repeated intensive exercise. / Med Sci Sports Exerc 1996, 28:450-56. CrossRef
  14. Baldari C, Videira M, Madeira F, Sergio J, Guidetti L: Lactate removal during active recovery related to the individual anaerobic and ventilatory thresholds in soccer players. / Eur J Appl Physiol 2004, 93:224-30. CrossRef
  15. Martin NA, Zoeller RF, Robertson RJ, Lephart SM: The comparative effects of sports massage, active recovery, and rest in promoting blood lactate clearance after supramaximal leg exercise. / J Athl Train 1998, 33:30-5.
  16. Howatson G, Goodall S, van Someren KA: The influence of cold water immersions on adaptation following a single bout of damaging exercise. / Eur J Appl Physiol 2009, 105:615-21. CrossRef
  17. Lattier G, Millet GY, Martin A, Martin V: Fatigue and recovery after high-intensity exercise. Part II: recovery interventions. / Int J Sports Med 2004, 25:509-15. CrossRef
  18. Leal Junior EC, Lopes-Martins RA, Dalan F, Ferrari M, Sbabo FM, Generosi RA, Baroni BM, Penna SC, Iversen VV, Bjordal JM: Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. / Photomed Laser Surg 2008, 26:419-24. CrossRef
  19. Leal Junior EC, Lopes-Martins RA, Vanin AA, Baroni BM, Grosselli D, De Marchi T, Iversen VV, Bjordal JM: Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. / Lasers Med Sci 2009, 24:425-31. CrossRef
  20. Leal Junior EC, Lopes-Martins RA, Rossi RP, De Marchi T, Baroni BM, de Godoi V, Marcos RL, Ramos L, Bjordal JM: Effect of cluster multi-diode light emitting diode therapy (LEDT) on exercise-induced skeletal muscle fatigue and skeletal muscle recovery in humans. / Lasers Surg Med 2009, 41:572-77. CrossRef
  21. Leal Junior EC, Lopes-Martins RA, de Almeida P, Ramos L, Iversen VV, Bjordal JM: Effect of low-level laser therapy (GaAs 904 nm) in skeletal muscle fatigue and biochemical markers of muscle damage in rats. / Eur J Appl Physiol 2010, 108:1083-088. CrossRef
  22. Leal Junior EC, Lopes-Martins RA, Frigo L, De Marchi T, Rossi RP, de Godoi V, Tomazoni SS, da Silva DP, Basso M, Lotti Filho P, Corsetti FV, Iversen VV, Bjordal JM: Effects of low-level laser therapy (LLLT) in the development of exercise-induced skeletal muscle fatigue and changes in biochemical markers related to post-exercise recovery. / J Orthop Sports Phys Ther 2010, 40:524-32. CrossRef
  23. De Marchi T, Leal Junior EC, Bortoli C, Tomazoni SS, Lopes-Martins RA, Salvador M: Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. / Lasers Med Sci 2012, 27:231-36. CrossRef
  24. Almeida P, Lopes-Martins RA, De Marchi T, Tomazoni SS, Albertini R, Corrêa JC, Rossi RP, Machado GP, da Silva DP, Bjordal JM, Leal Junior EC: Red (660 nm) and infrared (830 nm) low-level laser therapy in skeletal muscle fatigue in humans: what is better? / Lasers Med Sci 2012, 27:453-58. CrossRef
  25. Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Rossi RP, Grosselli D, Generosi RA, de Godoi V, Basso M, Mancalossi JL, Bjordal JM: Comparison between single-diode low-level laser therapy (LLLT) and LED multi-diode (cluster) therapy (LEDT) applications before high-intensity exercise. / Photomed Laser Surg 2009, 27:617-23. CrossRef
  26. Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Taufer D, Manfro DS, Rech M, Danna V, Grosselli D, Generosi RA, Marcos RL, Ramos L, Bjordal JM: Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. / Lasers Med Sci 2009, 24:857-63. CrossRef
  27. Leal Junior EC, de Godoi V, Mancalossi JL, Rossi RP, De Marchi T, Parente M, Grosselli D, Generosi RA, Basso M, Frigo L, Tomazoni SS, Bjordal JM, Lopes-Martins RA: Comparison between cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes: preliminary results. / Lasers Med Sci 2011, 26:493-01. CrossRef
  28. Baroni BM, Leal Junior EC, De Marchi T, Lopes AL, Salvador M, Vaz MA: Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. / Eur J Appl Physiol 2010, 110:789-96. CrossRef
  29. Joensen J, Demmink JH, Johnson MI, Iversen VV, Lopes-Martins RAB, Bjordal JM: The thermal effects of therapeuticl with 810 and 904 nm wavelengths on human skin. / Photomed and Laser Surg 2011, 29:145-53. CrossRef
  30. Malm C: Exercise-induced muscle damage and inflammation: fact or fiction? / Acta Physiol Scand 2001, 171:233-39. CrossRef
  31. Huang YY, Chen AC, Carrol JD, Hamblim MR: Biphasic dose response in low level light therapy. / Dose Response 2009, 7:358-83. CrossRef
  32. Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM: Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. / Lancet 1897-908, 2009:374.
  33. World Association for Laser Therapy (WALT): / Dosage Recommendations. Recommended Treatment Doses for Low Level Laser Therapy. Barcelona: WALT; 2010.
  34. Leal-Junior EC, Vanin AA, Miranda EF, De Carvalho PT, Dal Corso S, Bjordal JM: Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. / Lasers Med Sci 2013. doi:10.1007/s10103-13-465-
  
• 作者单位：Adriano Rodrigues de Oliveira (5)
  Adriane Aver Vanin (6)
  Thiago De Marchi (5)
  Fernanda Colella Antonialli (6)
  Vanessa dos Santos Grandinetti (5)
  Paulo Roberto Vicente de Paiva (5)
  Gianna Móes Albuquerque Pontes (5)
  Larissa Aline Santos (6)
  Ivo de Oliveira Aleixo Junior (6)
  Paulo de Tarso Camillo de Carvalho (5) (6)
  Jan Magnus Bjordal (6)
  Ernesto Cesar Pinto Leal-Junior (5) (6)
  
  5. Sports Medicine Institute, University of Caxias do Sul, Rua Francisco Getulio Vargas 1130, Caxias do Sul, RS, 95070-560, Brazil
  6. Physiotherapy Research Group, Faculty of Medicine and Dentistry, University of Bergen, Kalfarveien 31, Bergen, 5020, Norway
  
• ISSN：1745-6215

文摘

Background Recent studies involving phototherapy applied prior to exercise have demonstrated positive results regarding the attenuation of muscle fatigue and the expression of biochemical markers associated with recovery. However, a number of factors remain unknown, such as the ideal dose and application parameters, mechanisms of action and long-term effects on muscle recovery. The aims of the proposed project are to evaluate the long-term effects of low-level laser therapy on post-exercise musculoskeletal recovery and identify the best dose andapplication power/irradiation time. Design and methods A double-blind, randomized, placebo-controlled clinical trial with be conducted. After fulfilling the eligibility criteria, 28 high-performance athletes will be allocated to four groups of seven volunteers each. In phase 1, the laser power will be 200 mW and different doses will be tested: Group A (2 J), Group B (6 J), Group C (10 J) and Group D (0 J). In phase 2, the best dose obtained in phase 1 will be used with the same distribution of the volunteers, but with different powers: Group A (100 mW), Group B (200 mW), Group C (400 mW) and Group D (0 mW). The isokinetic test will be performed based on maximum voluntary contraction prior to the application of the laser and after the eccentric contraction protocol, which will also be performed using the isokinetic dynamometer. The following variables related to physical performance will be analyzed: peak torque/maximum voluntary contraction, delayed onset muscle soreness (algometer), biochemical markers of muscle damage, inflammation and oxidative stress. Discussion Our intention, is to determine optimal laser therapy application parameters capable of slowing down the physiological muscle fatigue process, reducing injuries or micro-injuries in skeletal muscle stemming from physical exertion and accelerating post-exercise muscle recovery. We believe that, unlike drug therapy, LLLT has a biphasic dose–response pattern. Trial registration The protocol for this study is registered with the Protocol Registry System, ClinicalTrials.gov identifier NCT01844271.