Comparison between laser therapy and non-surgical therapy for periodontitis in rats treated with dexamethasone

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• 作者：Valdir Gouveia Garcia ; Leandro Ara¨²jo Fernandes ; Juliano Milanezi de Almeida ; ¨¢lvaro Francisco Bosco ; Maria Jos¨¦ Hitomi Nagata ; Thiago Marchi Martins ; Tetuo Okamoto and Leticia Helena Theodoro
• 关键词：Periodontal disease ; Dexamethasone ; Laser ; Non ; surgical periodontal therapy
• 刊名：Lasers in Medical Science
• 出版年：2010
• 出版时间：March, 2010
• 年：2010
• 卷：25
• 期：2
• 页码：197-206
• 全文大小：539.9 KB

文摘

The aim of this study was to compare low-level laser therapy (LLLT) as adjuvant treatment for induced periodontitis with scaling and root planing (SRP) in dexamethasone-treated rats. One-hundred twenty rats were divided into groups: D group (n = 60), treated with dexamethasone; ND group (n = 60) treated with saline solution. In both groups, periodontal disease was induced by ligature at the left first mandibular molar. After 7 days, the ligature was removed and all animals were subjected to SRP and were divided according to the following treatments: SRP, irrigation with saline solution (SS); SRP + LLLT, SS and laser irradiation (660 nm; 24 J; 0.428 W/cm2). Ten animals in each treatment were killed after 7 days, 15 days and 30 days. The radiographic and histometric values were statistically analyzed. In all groups radiographic and histometric analysis showed less bone loss (P < 0.05) in animals treated with SRP + LLLT in all experimental periods. SRP + LLLT was an effective adjuvant conventional treatment for periodontitis in rats treated with dexamethasone.