Vascular Inflammation Imaging in Psoriasis

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• 作者：Abhishek Chaturvedi ; Amit K. Dey ; Aditya A. Joshi…
• 关键词：Psoriasis ; Vascular inflammation ; Arterial inflammation ; Atherosclerosis ; FDG PET CT
• 刊名：Current Cardiovascular Imaging Reports
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：10
• 期：2
• 全文大小：
• 刊物主题：Cardiology; Imaging / Radiology; Diagnostic Radiology; Interventional Radiology; Ultrasound; Nuclear Medicine;
• 出版者：Springer US
• ISSN：1941-9074
• 卷排序：10

文摘

Purpose of ReviewPsoriasis is a common, chronic inflammatory skin disease driven by immune dysregulation involving helper T cell 17 pathways. Psoriasis is associated with systemic inflammation, which increases the risk of joint disease (psoriatic arthritis), subclinical cardiovascular disease, and major adverse cardiovascular events, especially in young patients with severe skin disease. Furthermore, vascular inflammation by 18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) provides a valuable tool with utility in predicting future cardiovascular events. As such, psoriasis provides a clinical human model to characterize the vascular disease by non-invasive imaging techniques such as vascular inflammation by FDG PET/CT.