B cell sub-types following acute malaria and associations with clinical immunity
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- 作者：Richard T. Sullivan ; Isaac Ssewanyana ; Samuel Wamala ; Felistas Nankya…
- 关键词：Atypical memory B cells ; Transitional B cells ; Plasmablasts ; Plasma cells Plasmodium falciparum ; Malaria ; Immunity
- 刊名：Malaria Journal
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：15
- 期：1
- 全文大小：2,204 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Background Repeated exposure to Plasmodium falciparum is associated with perturbations in B cell sub-set homeostasis, including expansion atypical memory B cells. However, B cell perturbations immediately following acute malaria infection have been poorly characterized, especially with regard to their relationship with immunity to malaria.