High TUG1 expression is associated with chemotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

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• 作者：Lin Jiang ; Wenchao Wang ; Guoli Li ; Canlin Sun…
• 刊名：Cancer Chemotherapy and Pharmacology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：78
• 期：2
• 页码：333-339
• 全文大小：672 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Cancer Research
  Pharmacology and Toxicology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0843
• 卷排序：78

文摘

PurposeLong noncoding RNAs (lncRNAs) play critical roles in diverse biological processes such as tumorigenesis and metastasis. Taurine upregulated gene 1 (TUG1) is a cancer-related lncRNA that is associated with chromatin-modifying complexes and plays an important role in gene regulation. In this study, we determined the expression patterns of TUG1 in esophageal squamous cell carcinoma (ESCC) and evaluated its clinical significance.