Micromechanical properties of hydrogels measured with MEMS resonant sensors

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• 作者：Elise A. Corbin (1) (2)
  Larry J. Millet (2)
  James H. Pikul (1)
  Curtis L. Johnson (1)
  John G. Georgiadis (1)
  William P. King (1) (2)
  Rashid Bashir (2) (3)
  
• 关键词：MEMS mass sensor ; Electrohydrodynamic jet printing ; Polyethylene glycol ; Mass ; spring ; damper system ; Hydrogel micromechanics
• 刊名：Biomedical Microdevices
• 出版年：2013
• 出版时间：April 2013
• 年：2013
• 卷：15
• 期：2
• 页码：311-319
• 全文大小：546KB
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• 作者单位：Elise A. Corbin (1) (2)
  Larry J. Millet (2)
  James H. Pikul (1)
  Curtis L. Johnson (1)
  John G. Georgiadis (1)
  William P. King (1) (2)
  Rashid Bashir (2) (3)
  
  1. Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA
  2. Micro and Nanotechnology Laboratory, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA
  3. Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA
  
• ISSN：1572-8781

文摘

Hydrogels have gained wide usage in a range of biomedical applications because of their biocompatibility and the ability to finely tune their properties, including viscoelasticity. The use of hydrogels on the microscale is increasingly important for the development of drug delivery techniques and cellular microenvironments, though the ability to accurately characterize their micromechanical properties is limited. Here we demonstrate the use of microelectromechanical systems (MEMS) resonant sensors to estimate the properties of poly(ethylene glycol) diacrylate (PEGDA) microstructures over a range of concentrations. These microstructures are integrated on the sensors by deposition using electrohydrodynamic jet printing. Estimated properties agree well with independent measurements made using indentation with atomic force microscopy.