Association between Val66Met polymorphisms in brain-derived neurotrophic factor gene and asthma risk: a meta-analysis

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• 作者：Xinming Xie ; Yanting Zhu ; Jiaojiao Zhang ; Cui Zhai ; Wei Feng…
• 关键词：BDNF ; Polymorphism ; Asthma ; Meta ; analysis
• 刊名：Inflammation Research
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：64
• 期：11
• 页码：875-883
• 全文大小：894 KB
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• 作者单位：Xinming Xie (1)
  Yanting Zhu (1)
  Jiaojiao Zhang (2)
  Cui Zhai (1)
  Wei Feng (1)
  Yilin Pan (1)
  Lu Liu (1)
  Xiaofan Su (1)
  Lan Yang (1)
  Manxiang Li (1)
  
  1. Department of Respiratory Medicine, The First Affiliated Hospital of Medical College, Xi鈥檃n Jiaotong University, No.277, West Yanta Road, 710061, Xi鈥檃n, Shaanxi, People鈥檚 Republic of China
  2. Department of Pathology, The First Affiliated Hospital of Medical College, Xi鈥檃n Jiaotong University, Xi鈥檃n, China
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Immunology
  Pharmacology and Toxicology
  Allergology
  Dermatology
  Neurology
  Rheumatology
  
• 出版者：Birkh盲user Basel
• ISSN：1420-908X

文摘

Objective The Val66Met polymorphisms in brain-derived neurotrophic factor (BDNF) gene have been reported to be associated with asthma risk, while the results are inconclusive. Considering a single study may lack the power to provide reliable conclusion, we performed a meta-analysis to investigate the association between the Val66Met polymorphisms and asthma susceptibility.