MTB-specific lymphocyte responses are impaired in tuberculosis patients with pulmonary cavities

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• 作者：Jun Wang ; Yaping Dai ; Jun Liu ; Yongmei Yin ; Hao Pei
• 关键词：Cavity ; Tuberculosis ; TNF ; α ; IFN ; γ
• 刊名：European Journal of Medical Research
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：22
• 期：1
• 全文大小：1405KB
• 刊物主题：Medicine/Public Health, general; Infectious Diseases; Internal Medicine; Surgery; Oncology; Biomedicine, general;
• 出版者：BioMed Central
• ISSN：2047-783X
• 卷排序：22

文摘

ObjectiveTuberculosis (TB), an infectious disease caused by the bacillus Mycobacterium tuberculosis (MTB), is a global health problem. Because the failing immune response in the lung can lead to formation of a pulmonary cavity, this study was designed to clarify MTB-specific lymphocyte responses in TB patients with pulmonary cavities.