Reference levels of blood mercury and association with metabolic syndrome in Korean adults
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- 作者：Sang-Yong Eom (1)
Sun-Hee Choi (2)
Su-Ju Ahn (2)
Dong-Kyeong Kim (2)
Dong-Won Kim (2)
Ji-Ae Lim (3)
Byung-Sun Choi (2)
Hye-Jung Shin (4)
Sin-Weon Yun (5)
Hae-Jung Yoon (6)
Yu-Mi Kim (7)
Young-Seoub Hong (7)
Yong-Woon Yun (8)
Seok-Joon Sohn (8)
Heon Kim (1)
Kyung-Su Park (9)
Hee-Soo Pyo (10)
Ho Kim (11)
Se-Young Oh (12)
Jeongseon Kim (13)
Sang-Ah Lee (14)
Mina Ha (3)
Ho-Jang Kwon (3)
Jung-Duck Park (2) - 关键词：Blood Hg ; Risk factor ; Metabolic syndrome ; Cardiovascular diseases ; Korean adult
- 刊名：International Archives of Occupational and Environmental Health
- 出版年：2014
- 出版时间：July 2014
- 年：2014
- 卷：87
- 期：5
- 页码：501-513
- 全文大小：
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Sun-Hee Choi (2)
Su-Ju Ahn (2)
Dong-Kyeong Kim (2)
Dong-Won Kim (2)
Ji-Ae Lim (3)
Byung-Sun Choi (2)
Hye-Jung Shin (4)
Sin-Weon Yun (5)
Hae-Jung Yoon (6)
Yu-Mi Kim (7)
Young-Seoub Hong (7)
Yong-Woon Yun (8)
Seok-Joon Sohn (8)
Heon Kim (1)
Kyung-Su Park (9)
Hee-Soo Pyo (10)
Ho Kim (11)
Se-Young Oh (12)
Jeongseon Kim (13)
Sang-Ah Lee (14)
Mina Ha (3)
Ho-Jang Kwon (3)
Jung-Duck Park (2)
1. Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea
2. Department of Preventive Medicine, College of Medicine, Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul, 156-756, Korea
3. Department of Preventive Medicine, College of Medicine, Dankook University, Cheonan, Korea
4. Department of Pediatrics, National Medical Center, Seoul, Korea
5. Department of Pediatrics, College of Medicine, Chung-Ang University, Seoul, Korea
6. Risk Analysis and Research Division, National Institute of Food and Drug Safety Evaluation, Cheongwon, Korea
7. Department of Preventive Medicine, College of Medicine, Dong-A University, Busan, Korea
8. Department of Preventive Medicine, College of Medicine, Chonnam National University, Gwangju, Korea
9. Nano-Photonics Research Center, Korea Institute of Science and Technology, Seoul, Korea
10. Biomolecules Function Research Center, Korea Institute of Science and Technology, Seoul, Korea
11. Department of Epidemiology and Biostatistics, School of Public health, Seoul National University, Seoul, Korea
12. Department of Food and Nutrition, College of Human Ecology, Kyung Hee University, Seoul, Korea
13. Cancer Epidemiology Branch, National Cancer Center, Goyang, Korea
14. Department of Preventive Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea - ISSN：1432-1246
文摘
Purpose Mercury (Hg) is a nonessential and toxic metal that is widely distributed in the environment. This study was performed to estimate the representative blood Hg level, to determine the contributing factors to Hg exposure, and to analyze the association of blood Hg with metabolic syndrome in Korean adults. Methods Mercury exposure is assessed by total Hg concentration in blood. A total of 2,114 healthy adults who have not been exposed to Hg occupationally were sampled by the multistaged, sex-, and age-stratified probability method. Information was collected regarding the subjects-demographic characteristics, lifestyles, and past medical history. The participants then underwent physical examination and blood sampling. Results The geometric mean concentration of Hg in whole blood was 3.90?μg/L, which was significantly influenced by sex, age, smoking, alcoholic consumption, residence area, and seafood intake after adjustment for confounders. Significant increases in body mass index, waist circumference, diastolic blood pressure, total cholesterol, and triglyceride were observed according to the blood Hg levels after adjustment for covariates. Also, Hg exposure was significantly associated with metabolic syndrome and their components such as obesity and increased fasting glucose. Conclusion The blood Hg level in Korean adults is higher than that in USA and other Western countries, while it is similar to or lower than that in other Asian countries. The blood Hg level is influenced by sociodemographic factors and individual lifestyles including dietary habits. Furthermore, blood Hg is associated with metabolic syndrome, in which Hg exposure may play a role as a possible risk factor for cardiovascular diseases.