刊物主题:Internal Medicine; Metabolic Diseases; Human Physiology;
出版者:Springer Berlin Heidelberg
ISSN:1432-0428
卷排序:60
文摘
Aims/hypothesisAssessment of urinary extracellular vesicles including exosomes and microparticles (MPs) is an emerging approach for non-invasive detection of renal injury. We have previously reported that podocyte-derived MPs are increased in diabetic mice in advance of albuminuria. Here, we hypothesised that type 1 diabetes and acute hyperglycaemia would increase urinary podocyte MP levels in uncomplicated diabetes.