Evaluation of the Hypoglycemic Effect of Composite Rice Flour in Diabetic Mice

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• 作者：Zhigang Ding ; Hongmei Gao ; Chuanlai Du ; Yimei Zheng…
• 关键词：Hypoglycemic ; Diabetic ; Composite rice ; Glucose tolerance
• 刊名：Cell Biochemistry and Biophysics
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：74
• 期：1
• 页码：79-84
• 全文大小：439 KB
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• 作者单位：Zhigang Ding (1)
  Hongmei Gao (1)
  Chuanlai Du (1)
  Yimei Zheng (2)
  Yuanxin Guo (1)
  Dongmei Pan (1)
  
  1. Anhui Science and Technology University Institute of Food and Drug, Donghua Road No. 9, Feng-Yang Anhui, 233100, China
  2. Minnan Normal University School of Biological Science and Biotechnology, Fujian Province Zhangzhou County Front Street No. 36, Zhangzhou Fujian, 363000, China
  
• 刊物主题：Biochemistry, general; Pharmacology/Toxicology; Biotechnology; Cell Biology; Biophysics and Biological Physics;
• 出版者：Springer US
• ISSN：1559-0283

文摘

To study the hypoglycemic effect of composite rice flour, the diabetic mouse model was established through the intraperitoneal injection of alloxan saline (twice, 200 mg/kg bw). The mice were randomly divided into 4 groups: negative control, positive control, metformin medication group, and composite rice flour feed group. After 21 days, the fasting blood glucose levels were determined by glucose oxidase method and followed with a glucose tolerance test. The results show that the body weight growth rate of mice in the rice flour group was significantly higher than that of the medication group (P < 0.01). Comparing with the positive control group, the fasting blood glucose levels of medication group and rice flour group were significantly lower, and the glucose tolerance was significantly increased in rice flour group (P < 0.01). In conclusion, the composite rice flour has obvious hypoglycemic and protective effect for diabetic mouse model.