Improving the outcome of fractional CO2 laser resurfacing using a probiotic skin cream: Preliminary clinical evaluation
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- 作者：Giovanni Zoccali ; Benedetta Cinque ; Cristina La Torre…
- 关键词：CO2 laser ; Fractional resurfacing ; Inflammatory reaction ; Probiotics
- 刊名：Lasers in Medical Science
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：31
- 期：8
- 页码：1607-1611
- 全文大小：369 KB
- 刊物类别：Medicine
- 刊物主题：Medicine & Public Health
Medicine/Public Health, general
Dentistry
Laser Technology and Physics and Photonics
Quantum Optics, Quantum Electronics and Nonlinear Optics
Applied Optics, Optoelectronics and Optical Devices - 出版者：Springer London
- ISSN：1435-604X
- 卷排序：31
文摘
As known, fractional CO2 resurfacing treatments are more effective than non-ablative ones against aging signs, but post-operative redness and swelling prolong the overall downtime requiring up to steroid administration in order to reduce these local systems. In the last years, an increasing interest has been focused on the possible use of probiotics for treating inflammatory and allergic conditions suggesting that they can exert profound beneficial effects on skin homeostasis. In this work, the Authors report their experience on fractional CO2 laser resurfacing and provide the results of a new post-operative topical treatment with an experimental cream containing probiotic-derived active principles potentially able to modulate the inflammatory reaction associated to laser-treatment. The cream containing DermaACB (CERABEST™) was administered post-operatively to 42 consecutive patients who were treated with fractional CO2 laser. All patients adopted the cream twice a day for 2 weeks. Grades were given according to outcome scale. The efficacy of the cream containing DermaACB was evaluated comparing the rate of post-operative signs vanishing with a control group of 20 patients topically treated with an antibiotic cream and a hyaluronic acid based cream. Results registered with the experimental treatment were good in 22 patients, moderate in 17, and poor in 3 cases. Patients using the study cream took an average time of 14.3 days for erythema resolution and 9.3 days for swelling vanishing. The post-operative administration of the cream containing DermaACB induces a quicker reduction of post-operative erythema and swelling when compared to a standard treatment.