An efficient synthesis of new 1-H-4′-methyl-3′,4′-dihydrospiro[piperidine-4,2′(1′H)quinoline] scaffolds
- 作者：Leonor Y. Vargas Mé ; ndez ; Vladimir V. Kouznetsov
- 关键词：Spiro-4-piperidines ; Intramolecular alkene Friedel– ; Crafts alkylation ; 3′ ; 4′ ; -Dihydrospiro[piperidine-4 ; 2′ ; (1′ ; H)quinolines]
- 刊名：Tetrahedron Letters
- 出版年：2007
- 期刊代码：109_00404039
- 类别：ch
- 出版时间：2 April 2007
- 卷：48
- 期：14
- 页码：2509-2512
- 文件大小：121 K
摘要
Efficient synthesis of new 3′,4′-dihydrospiro[piperidine-4,2′(1′H)quinolines] by a four step synthetic route based on 1-benzyl-4-piperidone reactivity is reported.