In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae

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• 作者：Marí ; a Guinea^a ; ^{maria.guinea@uah.es} ; Virginia Franco^a ; Lidia Araujo-Baz&#225 ; n^b ; Iv&#225 ; n Rodrí ; guez-Martí ; n^b ; Salvador Gonz&#225 ; lez^c ; ^d
• 关键词：UVB photoprotection ; Zebrafish embryos ; Seaweed polyphenols ; Ochrophyta ; Rhodophyta ; Total phenolic content (TPC)
• 刊名：Food and Chemical Toxicology
• 出版年：2012
• 期刊代码：20_02786915
• 类别：pha
• 出版时间：March-April, 2012
• 卷：50
• 期：3-4
• 页码：1109-1117
• 文件大小：911 K

摘要

The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE.