摘要
Purpose
To evaluate prospectively the correlation of scar-formations after vacuum-assisted biopsy with different systems and needle-sizes and interventional bleeding/post-interventional hematoma.Methods and materials
<p>Between 01/2008 and 12/2009, 479 patients underwent vacuum-assisted biopsy under stereotactic-guidance, using the Mammotomep>庐p>-system with 11/8-gauge and ATECp>庐p>-system with 12/9-gauge, whereas in 178 cases with representative benign histology no surgical-biopsy after vacuum-assisted biopsy was performed and at least a 2-plane-follow-up-mammogram after 6 month post-vacuum-assisted biopsy was available. Bleeding during intervention, hematoma post-intervention and scar-tissue was scored as minimal and moderate/severe. Statistical analysis included Chi-Square-trend-test, p-value <0.05 was considered to be significant.Results
<p>Significantly more bleedings and post-interventional hematomas for 8-gauge-Mammotomep>庐p>-system vs. 11-gauge-Mammotomep>庐p>-system (41.9%vs. 8.4%, p < 0.001/35.5%vs. 16.7%, p = 0.029), no significant-differences for the ATECp>庐p>-systems 9-gauge vs. 12-gauge (26.9%vs. 29.7%, p = 0.799/42.3%vs. 43.2%, p = 0.596). 11-gauge-Mammotomep>庐p>-system vs. ATECp>庐p>-12-gauge-system revealed significantly less bleedings/hematomas (8.4%vs. 29.7%, p = 0.015/16.7%vs. 43.2%, p = 0.001), no significant differences for the large-systems (p = 0.135/p = 0.352). Follow-up of Mammotomep>庐p>-11/8-gauge-system system has shown 13.1/16.1%minimal scar-formation and 1.2/3.2%moderate/severe scars, whereas ATECp>庐p>-12/9-gauge-system has shown 10.8/3.8%minimal scar-formation and 0/11.5%moderate/severe scars, no significant differences. No significant difference was found when comparing Mammotomep>庐p>-11/8-g-systems vs. ATECp>庐p>-12/9-g-systems (p = 0.609/p = 0.823). There was also no correlation between risk of scar-formation after occurrence of bleeding or hematoma with any examined VAB-system or any needle size in this study (p = 0.800).Conclusion
<p>Using larger needle-sizes significantly (Mammotomep>庐)p>/not significant for ATECp>庐p>) more interventional bleedings and post-interventional hematomas were detected, only a tendency concerning scar-formation.
