• 作者：Pedro Abizanda Soler^a ; ^{pabizanda@sescam.jccm.es} ; Jesú ; s Ló ; pez-Torres Hidalgo^b ; Luis Romero Rizos^a ; Mercedes Ló ; pez Jimé ; nez^c ; Pedro Manuel Sá ; nchez Jurado^a ; Pilar Atienzar Nú ; ñ ; ez^a ; José ; Luis Esquinas Requena^a ; Inmaculada Garcí ; a Nogueras^a ; Pablo Herná ; ndez Zegarra^a ; Yadira Bardales Mas^a ; Ramona Campos Rosa^d ; Mercedes Martí ; nez Peñ ; alver^e ; Esther de la Osa Nieto^e ; Miriam Carió ; n Gonzá ; lez^e ; Á ; ngela Ruiz Gó ; mez^e ; Caridad Aguilar Cantos^e ; Pilar Mañ ; ueco Delicado^e ; José ; Luis Oliver Carbonell^e
• 关键词：Anciano fr&aacute ; gil ; Estudio de cohortes ; Razonamiento ; Dise&ntilde ; o ; Metodologí ; a
• 刊名：Revista Espa帽ola de Geriatr铆a y Gerontolog铆a
• 出版年：2011
• 期刊代码：pca313_0211139X
• 类别：med
• 出版时间：March-April 2011
• 卷：46
• 期：2
• 页码：81-88
• 文件大小：191 K

lass="h4">Objective

To obtain a cohort of subjects of equal to or greater than 70 years, representative of a Spanish urban population, to estimate the prevalence of frailty and follow it up over time to analyse associated factors.

lass="h4">Material and methods

A prospective, population-based cohort study. From a population of 18,137 elderly persons, a representative sample of 1172 was randomly stratified, of which 993 (84.7%) agreed to take part. The variables collected were; sociodemographic, comorbidity, functional (n = 825), cognitive, affective and quality of life. On the patients who agreed, body composition was determined by bioimpedance analysis (n = 557), basal metabolic rate by indirect calorimetry (n = 450) and a blood sample was obtained for biomarkers (n = 859). Frailty was defined by the presence of 3 or more Fried criteria: unintentional weight loss, low energy, exhaustion, slow walking, and low physical activity. The cohort will be followed up over time until the death of the subjects.

lass="h4">Results

Mean age 79.4 (SD 6.4) years, with 601 (60.5%) women. A total of 21.3%were institutionalised; 16.9%were frail, 48.5%pre-frail, 21.3%non-frail, and 12.8%did not have the 3 criteria to be able to determine their state, of which 9.5%had moderate-severe incapacity, which would increase the prevalence of frailty to 26.4%.

lass="h4">Conclusions

A FRADEA cohort has been constructed, representative of an urban population in Spain. The prevalence of frailty in the cohort was 16.9%.