• 作者：J.A. Ortega-Garcí ; a^a ; ^{ortega@pehsu.org} ; F.A. Ló ; pez-Herná ; ndez^b ; E. Sobrino-Najul^a ; I. Febo^a ; J.L. Fuster-Soler^c
• 关键词：Historia ambiental pedi&aacute ; trica ; C&aacute ; ncer infantil ; Etiologí ; a ; Agrupamientos
• 刊名：Anales de Pediatr铆a
• 出版年：2011
• 期刊代码：pca47_16954033
• 类别：med
• 出版时间：April 2011
• 卷：74
• 期：4
• 页码：255-260
• 文件大小：199 K

Introduction

Environment and Paediatric Cancer (PC) in the Region of Murcia (RM) is an on-going research project that has the following aims: to collect a careful paediatric environmental history (PEH) and to use geographical information systems (GIS) to map the incidence and analyze the geographic distribution of the PC incidence in the RM. The objectives are to present the methodology used for the collection and processing of data and disseminate initial results on the spatial and temporal incidence of PC in the RM (Spain).

Material and methods

A descriptive and georeference study of all PC cases under 15 years, diagnosed from 1 January 1998 to December 31, 2009. Three postal addresses were assigned to each case, residence during pregnancy, postnatal, and at the time of diagnosis. Other variables such as sex, date of birth, date of diagnosis, and histopathology classification were collected.

Results

No increase was observed in the trend of incidence of PC. The crude annual incidence rate was 14.3 cases per 100,000 children under 15 years. The standardised incidence ratio was higher in the north-west of the RM. Before diagnosis, 30%of cases had a different postal address than during the pregnancy.

Conclusions

Integrating the spatial and temporal information through the PEH in a GIS should allow the identification and study of space-time clusters through an environmental monitoring system in order to know the importance of associated risk factors.