Simultaneous detection of dopamine and acetaminophen by modified gold electrode with polypyrrole/aszophloxine film
- 作者：Mohammad Bagher Gholivand ; mbgholivand@yahoo.com ; Masoud Amiri
- 关键词：Polypyrrole ; Dopamine ; Acetaminophen ; Aszophloxine ; Modified electrode
- 刊名：Journal of Electroanalytical Chemistry
- 出版年：2012
- 期刊代码：pca22_15726657
- 类别：ce
- 出版时间：1 July, 2012
- 卷：676
- 期：Complete
- 页码：53-59
- 文件大小：794 K
摘要
The differential pulse voltammetric method was developed for simultaneous determination of dopamine (DA) and acetaminophen (AC) using the Ppyox/AZ/Au (poly overoxidized pyrrole-aszophloxine-gold) modified electrode. Polypyrrole film was prepared by incorporation of aszophloxine (AZ) as doping anion, during the electropolymerization of pyrrole onto a gold (Au) electrode in aqueous solution using the cyclic voltammetric (CV) technique. Then the polypyrrole film was overoxidized at constant potential. Well-separated voltammetric peaks were observed for dopamine (DA) and acetaminophen (AC) with peaks separation of about 200 mV. The current of the oxidation peaks showed a linear dependent on the concentrations of DA and AC in the range of 0.1-30 渭M and 0.2-100 渭M respectively. The detection limit of 0.05 and 0.08 渭M (S/N = 3) were obtained for DA and AC respectively. The modified electrode was used for determination of DA and AC in some real samples such as human serum and tablet samples.