Membrane-assisted extractive butanol fermentation by Clostridium saccharoperbutylacetonicum N1-4 with 1-dodecanol as the extractant

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• 作者：Shigemitsu Tanaka^a ; ¹ ; Yukihiro Tashiro^b ; ² ; Genta Kobayashi^a ; ^{gentak@cc.saga-u.ac.jp} ; Toru Ikegami^c ; Hideyuki Negishi^c ; Keiji Sakaki^c
• 关键词：Acetone&ndash ; butanol&ndash ; ethanol (ABE) fermentation ; Clostridium saccharoperbutylacetonicum N1-4 ; 1-Dodecanol ; Membrane-assisted extractive fermentation ; Polytetrafluoroethylene
• 刊名：Bioresource Technology
• 出版年：2012
• 期刊代码：11_09608524
• 类别：ce
• 出版时间：July, 2012
• 卷：116
• 期：Complete
• 页码：448-452
• 文件大小：266 K

摘要

A polytetrafluoroethylene (PTFE) membrane was used in membrane-assisted extractive (MAE) fermentation of acetone-butanol-ethanol (ABE) by Clostridium saccharoperbutylacetonicum N1-4. The growth inhibition effects of 1-dodecanol, which has a high partition coefficient for butanol, can be prevented by employing 1-dodecanol as an extractant when using a PTFE membrane. Compared to conventional fermentation, MAE-ABE fermentation with 1-dodecanol decreased butanol inhibition and increased glucose consumption from 59.4 to 86.0 g/L, and total butanol production increased from 16.0 to 20.1 g/L. The maximum butanol production rate increased from 0.817 to 0.979 g/L/h. The butanol productivity per membrane area was remarkably high with this system, i.e., 78.6 g/L/h/m². Therefore, it is expected that this MAE fermentation system can achieve footprint downsizing.