Cell adhesion to cathodic arc plasma deposited CrAlSiN thin films

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• 作者：Sun Kyu Kim^a ; ^{skim@ulsan.ac.kr} ; Vuong-Hung Pham^b ; Chong-Hyun Kim^c
• 关键词：Cell adhesion ; CrAlSiN thin films ; Focal contact adhesion ; Cell proliferation ; Actin cytoskeleton
• 刊名：Applied Surface Science
• 出版年：2012
• 期刊代码：6_01694332
• 类别：ms
• 出版时间：1 July, 2012
• 卷：258
• 期：18
• 页码：7202-7206
• 文件大小：893 K

摘要

Osteoblast cell response (cell adhesion, actin cytoskeleton and focal contact adhesion as well as cell proliferation) to CrN, CrAlSiN and Ti thin films was evaluated in vitro. Cell adhesion and actin stress fibers organization depended on the film composition significantly. Immunofluorescent staining of vinculin in osteoblast cells showed good focal contact adhesion on the CrAlSiN and Ti thin films but not on the CrN thin films. Cell proliferation was significantly greater on the CrAlSiN thin films as well as on Ti thin films than on the CrN thin films.