Effect of delayed umbilical cord clamping on blood gas analysis

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• 作者：Javier Valero ; Domingo Desantes ; Alfredo Perales-Puchalt ; Juan Rubio ; Vicente J. Diago Almela ; Alfredo Perales ; ^{perales_alf@gva.es}
• 关键词：Fetal monitoring ; Blood gas analysis ; Acid&ndash ; base equilibrium ; Umbilical cord ; Lactic acid ; Fetal blood
• 刊名：European Journal of Obstetrics and Gynecology and Reproductive Biology
• 出版年：2012
• 期刊代码：92_03012115
• 类别：med
• 出版时间：May, 2012
• 卷：162
• 期：1
• 页码：21-23
• 文件大小：139 K

摘要

Objective

To ascertain if there are differences in umbilical cord blood gas analysis between immediate and delayed cord clamping.

Study design

In a prospective observational study on 60 vaginally delivered healthy term newborns, we sampled umbilical cord blood immediately after delivery and at the time umbilical cord pulsation spontaneously ceased.

Results

There were significant decreases in pH, oxygen saturation (sO₂), glycemia, oxygen content (ctO₂), bicarbonate (HCO₃^{鈭?/sup>) and base excess (BE). Lactate and increased. Delayed cord clamping pH correlated with immediate cord clamping pH, , ctHb, sO₂ and time (r2 = 0.77, p < 0.000). Delayed cord clamping lactate was associated with immediate cord clamping lactate and time (r2 = 0.83, p < 0.000). Delayed BE was associated with previous pH, lactate, glycemia, ctHb and time (r2 = 0.83, p < 0.000).}

Conclusions

Delayed cord clamping alters acid-base parameters and lactate values compared to immediate cord clamping. Those variations depend mainly on time, prior pH and lactate.