• 作者：Carlos S&#225 ; nchez-Gonz&#225 ; lez^a ; ^{coxibum@hotmail.com} ; José ; F. Dí ; az-Fern&#225 ; ndez^a ; Manuel Jimé ; nez-Navarro^b ; Juan C. Fern&#225 ; ndez-Guerrero^c ; Juan H. Alonso Briales^b ; Antonio Gó ; mez Menchero^a ; Manuel F. Guzm&#225 ; n Herrera^c ; Rosa M. Cardenal-Piris^a ; José ; M. Hern&#225 ; ndez Garcí ; a^b
• 关键词：Intervencionismo percutá ; neo ; Tronco comú ; n ; Electivo ; Pronó ; stico
• 刊名：Cardiocore
• 出版年：2011
• 期刊代码：pca84_1889898X
• 类别：med
• 出版时间：October-December 2011
• 卷：46
• 期：4
• 页码：143-149
• 文件大小：362 K

Introduction and objective

Urgent intervention and cardiogenic shock are established as the main prognostic indicators in percutaneous revascularization of unprotected left main coronary disease. The outcome and identification of prognostic factors are less established for elective procedures. The purpose of this study is to assess the short and medium-term outcome after elective percutaneous coronary artery intervention for unprotected left main coronary disease.

Methods and results

A multicentre sample of 250 consecutive patients was included between January 2004 and March 2008. A high risk EuroScore was observed in 49.6%of cases. There was 0.4%hospital cardiac mortality and after a medium follow up of 19.6 months the rate of major adverse cardiac events was 18.4%(myocardial infarction 2.0%, target vessel revascularization 6.8%, cardiac mortality 9.6%). High risk EuroScore and implantation of two stents for left main lesion were identified as independent predictors of mayor adverse cardiac events during follow up (HR, 2.59; 95%CI, 1.35-5.00; P = .004 and HR, 2.05; 95%CI, 1.05-4.00; P = .035, respectively).

Conclusions

In our study elective percutaneous coronary intervention for unprotected left main disease is mainly performed on high risk patients resulting in a feasible procedure with favourable short and medium-term results. High risk EuroScore and implantation of two stents for left main lesion are identified as main predictors of events during follow up.