Anxiety is associated with impulsivity in bipolar disorder
- 作者：Charles T. Taylor ; Dina R. Hirshfeld-Becker ; Michael J. Ostacher ; C ; ice W. Chow ; Richard T. LeBeau ; Mark H. Pollack ; Andrew A. Nierenberg ; Naomi M. Simon
- 关键词：Bipolar disorder ; Anxiety disorder ; Anxiety ; Impulsivity ; Comorbidity ; Behavioral disinhibition
- 刊名：Journal of Anxiety Disorders
- 出版年：2008
- 期刊代码：142_08876185
- 类别：med
- 出版时间：June 2008
- 卷：22
- 期：5
- 页码：868-876
- 文件大小：150 K
摘要
Impulsivity and anxiety, common features of bipolar disorder (BD), are each associated with a number of negative outcomes in BD. The relationship between anxiety and impulsivity, however, has not been a focus of study in BD. In this paper, we present data regarding the association between anxiety and impulsivity as measured by the Barratt impulsiveness scale (BIS-11) in 114 outpatients with BD. Results revealed that patients with a comorbid anxiety disorder displayed significantly higher levels of impulsivity relative to patients without an anxiety disorder. Moreover, a broad range of anxiety-related symptom domains was associated with greater impulsivity. Exploratory analyses also revealed that baseline anxiety symptoms were associated with elevated impulsivity at 9-month follow-up, although these relationships were less robust after covariate adjustment. These data demonstrate that anxiety is positively associated with impulsivity in patients with BD. Further studies are needed to elucidate the implications of and reasons for this association.