Thirty two male Wistar rats were arranged in four groups: control, EMF exposed, movement restrained (MR), and EMF聽+ MR for 2 h. Rats were then sacrificed and their brains analyzed for superoxide dismutase and catalase activities, reduced glutathione, nitric oxide, total cholesterol, and triacylglycerol levels, as well as plasma corticosterone concentrations.
Acute exposure to EMF induces reduction in catalase and superoxide dismutase activities, whereas the combination of EMF聽+ MR also decreases both reduced glutathione and nitric oxide levels. Our results show that the acute exposure to EMF does not induce elevation of stress-hormone corticosterone but impairs the antioxidant status in rat brain.
Plasma corticosterone concentration and antioxidant data indicate that the acute exposure to EMF appears to be a mild stressor that leads to some adaptive responses due to the activation of systems controlling the brain oxidative balance.