First synthesis of 7-amido-[1,2,4]triazolo[1,5-a]pyrimidines using halogenȁ3;metal exchange
- 作者：Florian Montel ; Clemens Lamberth ; Pierre M.J. Jung
- 关键词：Model-based segmentation ; 4D CT images ; Respiratory phases ; Propagation of contours
- 刊名：Tetrahedron
- 出版年：2008
- 期刊代码：107_00404020
- 类别：ch
- 出版时间：30 June 2008
- 卷：64
- 期：27
- 页码：6372-6376
- 文件大小：435 K
摘要
A new and efficient methodology for the preparation of novel 7-carboxyl-triazolopyrimidine derivatives via the halogenȁ3;metal exchange is described. In addition, we showed that this new method can be useful for the synthesis of amides, esters, and ketones by using different carbamoyl chlorides, isocyanides or acyl chlorides as electrophile.