Synthesis of disazo pyrazolo[1,5-a]pyrimidines

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• 作者：Fikret Karc
  31 ; ; Aykut Demirç ; al
  31
• 关键词：Pyrazolopyrimidine ; Disazo ; Intermolecular cyclization ; Diazo-coupling reaction ; Condensation reaction
• 刊名：Dyes and Pigments
• 出版年：2007
• 期刊代码：31_01437208
• 类别：ms
• 出版时间：2007
• 卷：74
• 期：2
• 页码：288-297
• 文件大小：269 K

摘要

p-Substituted anilines were diazotized and coupled with 3-aminocrotononitrile, malononitrile, ethyl cyanoacetate or ethyl acetoacetate to give the 2-arylhydrazone-3-ketimino-butyronitriles, 2-arylhydrazonomalononitriles, ethyl 2-arylhydrazonocyanoacetates and ethyl 2-arylhydrazonoacetoacetates, respectively. Cyclization of these arylhydrazone derivatives with 5-amino-4-arylazo-3-methyl-1H-pyrazoles or 3,5-diamino-4-arylazo-1H-pyrazoles in pyridine moiety afforded the corresponding disazo pyrazolo[1,5-a]pyrimidine derivatives.