Primary orbital and adnexal non-Hodgkin lymphoma (POAL): a single centre study of 20 cases
摘要
The clinical behaviour, the prognosis and the treatment of the POAL are subject to some controversies. We define POAL as a localised lymphoma in the orbital and adnexal structures (IE), lasting at least one month after a diagnosis and complete staging procedure used in NHL. We studied 20 patients (pts) with lymphoproliferative lesions, from 1974 to 1994, finding 14 with POAL (orbit 6; lachrymal gland 4; conjunctive 2; eyelids 2), 1 patient had bilateral lesions. For the recent pts we studied the immunophenotype the beta2 microglobulin, LDH, abdominal ecography or CT, orbital CT or MRI. We applied the up-dated Kiel Classification (1 high grade and 13 low grade, most of them lymphoplasmocytic or diffuse centrocytic type cells). They was 2.5%of our NHL. The median age was 68 years (range 16-87) and there were a female predominance (M/F 1:2.5). No patients had monoclonal gammopathy or immune disorder. The initial presentation was ocular tumour or proptosis in all pts.