Organocatalytic and metal-mediated asymmetric [3 + 2] cycloaddition reactions

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• 作者：Yalan Xing^a  ; [Author Vitae] ; Nai-Xing Wang^b ; ^{nxwang@mail.ipc.ac.cn}  ; [Author Vitae]
• 关键词：[3  ; +  ; 2] cycloadditions ; 1 ; 3-Dipolar cycloaddition reactions ; Asymmetric cycloadditions ; Asymmetric catalysis ; Organocatalysts
• 刊名：Coordination Chemistry Reviews
• 出版年：2012
• 期刊代码：27_00108545
• 类别：ch
• 出版时间：June, 2012
• 卷：256
• 期：11-12
• 页码：938-952
• 文件大小：1395 K

摘要

This review focuses on recent progress in organocatalytic and metal-mediated asymmetric [3 + 2] cycloadditions, including 鈥榗lick鈥?chemistry, asymmetric 1,3-dipolar and asymmetric non-1,3-dipolar [3 + 2] cycloadditions. The theoretical aspects and synthetic applications of these organocatalytic and metal-mediated asymmetric [3 + 2] cycloadditions are summarized. In addition, an understanding of the mechanistic details which lead to efficient stereoselectivity in organocatalytic and metal-mediated asymmetric [3 + 2] cycloadditions is provided. Most of the references reviewed in this paper are from 2007 upto now.