Novel phytonutrient contributors to antioxidant protection against cardiovascular disease

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• 作者：Graziano Riccioni ; M.D. ; Ph.D.^a ; ^c ; ^{griccioni@hotmail.com} ; Lorenza Speranza ; Ph.D.^b ; Mirko Pesce ; Ph.D.^b ; Salvatore Cusenza ; Ph.D.^c ; Nicolantonio D&rsquo ; Orazio ; Prof.^c ; Michael J. Glade ; M.D.^d
• 关键词：Oxidative stress ; Vitamins ; Carotenoids ; Flavonoids ; Atherosclerosis ; Cardiovascular risk ; Oxidized low-density lipoprotein
• 刊名：Nutrition
• 出版年：2012
• 期刊代码：81_08999007
• 类别：abs
• 出版时间：June, 2012
• 卷：28
• 期：6
• 页码：605-610
• 文件大小：225 K

摘要

The associations linking endothelial inflammation, endothelial oxidative stress, and atherogenesis and the potential for dietary phytonutrients to decrease the impact of these associations were assessed. A detailed literature review was conducted and summarized. A large body of scientific evidence describes the interactions among endothelial inflammation, endothelial oxidative stress, and atherogenesis. A growing body of research indicates that several dietary phytonutrients (astaxanthin, lycopene, lutein, and glabridin) can decrease the risk for atherosclerosis by decreasing endothelial inflammation and oxidative stress. The consumption of foods or dietary supplements that provide astaxanthin, lycopene, lutein, and glabridin can ameliorate endothelial inflammation and oxidative stress, retard atherogenesis, and decrease the risk for atherogenic cardiovascular disease.