Prevention through Design (PtD): History and Future
- 作者：Fred A. Manuele
- 关键词：Competitive nonlinear pricing ; Delegation principle ; Catalog games ; Farsighted stability
- 刊名：Journal of Safety Research
- 出版年：2008
- 期刊代码：108_00224375
- 类别：et
- 出版时间：2008
- 卷：39
- 期：2
- 页码：127-130
- 文件大小：89 K
摘要
Processing pediatric neuroimaging data is a challenge due to pervasive morphological changes that occur in the human brain during normal development. This is of special relevance when reference data is used as part of the processing approach, as in spatial normalization and tissue segmentation. Current approaches construct reference data (templates) by averaging brain images from a control group of subjects, or by creating custom templates from the group under study. In this technical note, we describe a new, and generalized method of constructing such appropriate reference data by statistically analyzing a large sample (n = 404) of healthy children, as acquired during the NIH MRI study of normal brain development.