Food-borne diseases caused by
Salmonella enterica are a significant public health concern around the world. Since 2002,
S. enterica serovar Kentucky has shown an increase in several countries with the concurrent emergence of multidrug-resistant isolates. The spread of such strains in the environment poses a major public health problem. A total of 57
Salmonella Kentucky strains isolated from different sources during the period 2005 to 2008 in Tunisia, were characterized by their antimicrobial and mercury resistance profiles; ability to form a biofilm; virulence
invA/spvC genes and quorum sensing
sdiA gene. A total of 10.6%of the isolates demonstrated multidrug-resistance against 3 to 13 antibiotics with ciprofloxacin resistance occurring in 33%of human isolates. In addition, 37%of the isolates exhibited minimum inhibitory concentrations value to mercuric chloride, ranging from 8 to 32 渭g ml
鈭? and were considered as resistant strains. The majority of strains tested were able to form a biofilm, especially for environmental and animal derived isolates. Therefore, the biofilm seems to comprise a normal and favorable capability in the life of
Salmonella Kentucky in the environment. Interestingly, all the isolates possessed the
sdiA gene, 87.7%of isolates possessed the
invA gene, and no isolate harbored the
spvC gene.
The emergence of resistance to ciprofloxacin in human Salmonella Kentucky isolates, added to the presence of invA and sdiA genes, and the production of biofilm could be the decisive factors in the dissemination of S. Kentucky strains on a large scale.