Efficient and tunable synthesis of new polydentate bifunctional chelating agents using click chemistry

详细信息	查看全文 | 推荐本文 |

• 作者：Clé ; ment Camp ; S ; ra Dorbes ; Claude Picard ; Eric Benoist
• 关键词：Polydentate chelating agents ; Bifunctional chelator ; Click chemistry ; Triazole
• 刊名：Tetrahedron Letters
• 出版年：2008
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：17 March 2008
• 卷：49
• 期：12
• 页码：1979-1983
• 文件大小：127 K

摘要

Two novel bifunctional chelating agents, which are bistriazole-based polyaminocarboxylic acids, have been designed and synthesised in high yields. An elegant synthetic approach using the Cu-catalysed azide–alkyne cycloaddition has been developed. This convenient route could be employed for the synthesis of a variety of polydentate bifunctional chelators.