Psychological stress as a risk factor for postoperative keloid recurrence

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• 作者：Fabianne Furtado ; Bernardo Hochman ; ^{bernardohochman@uol.com.br} ; ^{bibifst@yahoo.com.br} ; Paulo Luiz Farber ; Marisa Campio Muller ; Lilian Fukusima Hayashi ; Lydia Masako Ferreira
• 关键词：Galvanic skin response ; Keloid ; Prognosis ; Psychological stress ; Recurrence
• 刊名：Journal of Psychosomatic Research
• 出版年：2012
• 期刊代码：170_00223999
• 类别：med
• 出版时间：April, 2012
• 卷：72
• 期：4
• 页码：282-287
• 文件大小：356 K

摘要

Objective

To investigate psychological stress on the prognosis of the postoperative recurrence of keloids.

Methods

Patients with keloids (n = 25), candidates for surgical resection and postoperative radiotherapy, had their psychological stress evaluated on the day before the surgical procedure. The parameters evaluated were pain and itching (Visual Numerical Scale), quality of life (Questionnaire QualiFibro/Cirurgia Pl谩stica-UNIFESP), perceived stress (Perceived Stress Scale), depression and anxiety (Hospital Depression and Anxiety Scale), salivary cortisol and minimum and maximum galvanic skin responses (GSR) at rest and under stress (i.e., while the questionnaires were being filled out). Patients were evaluated during the 3rd, 6th, 9th and 12th months of postoperative care. During each return visit, two experts classified the lesions as non-recurrent and recurrent.

Results

The recurrence group presented the greatest values in GSR during a stressful situation. The chance of recurrence increased by 34%at each increase of 1000 arbitrary units in maximum GSR during stress.

Conclusion

Psychological stress influenced the recurrence of keloids.